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Proof of Concept Study: Comparison of Semi-Automated RNA Isolation Methods from Archived Formalin-Fixed, Paraffin-Embedded Tissues with Clinical Routine RNA Isolation Methods.
Methods Protoc
December 2024
Department of Pathology, Herlev University Hospital, 2730 Herlev, Denmark.
High-quality RNA is crucial in clinical diagnostics and precision medicine. Formalin-fixed and paraffin-embedded (FFPE) tissues pose a challenge due to nucleic acid fragmentation and crosslinking. In this pilot study, various commercially available techniques for extracting RNA from small FFPE samples were compared.
View Article and Find Full Text PDFRobot-Assisted Myomectomy versus Open Surgery : Cost-Effectiveness analysis: Cost-Effectiveness of Robotic Myomectomy.
J Gynecol Obstet Hum Reprod
December 2024
Assistance Publique-Hospitals of Paris, Department of Gynecological and Breast Surgery and Oncology, Pitié Salpêtrière Hospital, Paris, France; University Institute of Cancer (IUC), AP-HP, Sorbonne University, Paris, France; Saint-Antoine Research Center (CRSA), INSERM UMR_S_938, Biology and Therapeutics of Cancer, Sorbonne University, Paris, France. Electronic address:
Introduction: Fibroids are the most common benign uterine tumors. There are different possibilities for surgical approaches, and evaluating the cost of these operations is fundamental in modern surgery. The aim of our study is to evaluate the cost-effectiveness of robotic-assisted myomectomy (RAM) compared to open myomectomy (OM) in France.
View Article and Find Full Text PDFModel based on ultrasound and clinicopathological characteristics for early prediction of pathological complete response to neoadjuvant chemotherapy in breast cancer.
Quant Imaging Med Surg
December 2024
Department of Ultrasound, the Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China.
Background: Accurate assessment of pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer (BC) is crucial for mitigating chemotherapy-related toxicity in patients who do not respond to the treatment. Conventional ultrasound (US) has become a pivotal method for evaluating treatment response due to its cost-effectiveness, convenience, and absence of ionizing radiation. The objective of this study was to develop a model combining US and clinicopathological characteristics at baseline, as well as US features after one cycle of NAC, to predict the pCR to NAC in BC.
View Article and Find Full Text PDFElectrical Stimulation Therapy - Dedicated to the Perfect Plastic Repair.
Adv Sci (Weinh)
December 2024
Department of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Article Synopsis
- * The review covers different sources of electrical stimulation and the best electrode materials suited for clinical applications, discussing their biological impacts on cells and tissues.
- * Future developments will focus on improving equipment performance and meeting clinical needs, emphasizing the importance of safety, feasibility, and cost-effectiveness in these technologies.
Bibliometric Analysis of Comprehensive Geriatric Assessment from 2004 to 2023.
J Multidiscip Healthc
December 2024
Department of Dermatology, Beijing Hospital, National Center of Gerontology, Beijing, China; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, People's Republic of China.
Background: The global aging population necessitates specialized tools for complex geriatric health issues. Comprehensive Geriatric Assessment (CGA) provides multidimensional evaluations of elderly, integrating inputs from various professionals to create individualized care plans. This study aims to visually assess the research trends and hotspots in the field of CGA, review mainstream perspectives in this field, and provide a foundation for future research and treatment.
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