Use of transcranial magnetic stimulation in the treatment of nonfluent primary progressive aphasia: a case report.

Dement Neuropsychol

Universidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Centro para Doença de Alzheimer, Rio de Janeiro RJ, Brazil.

Published: December 2023

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Article Abstract

Primary progressive aphasia comprises a group of neurodegenerative diseases characterized by progressive speech and language dysfunction. Neuroimaging (structural and functional), biomarkers, and neuropsychological assessments allow for early diagnosis. However, there is no pharmacological treatment for the disease. Speech and language therapy is the main rehabilitation strategy. In this case report, we describe a female patient diagnosed with nonfluent primary progressive aphasia who underwent sessions of high-frequency transcranial magnetic stimulation in the left dorsolateral prefrontal cortex and showed improvement in depression scores, naming tasks in oral and written speech, and comprehension tasks in oral and written discourse.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10695438PMC
http://dx.doi.org/10.1590/1980-5764-DN-2023-0021DOI Listing

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