[Polypharmacy in patients with dementia].

Inn Med (Heidelb)

Krankenhausapotheke, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Published: January 2024

The number of patients with dementia is expected to grow in the coming years due to an aging population and an increasing life-expectancy. At the same time, in an aging society there will be an increase in multimorbidity and therefore polypharmacy. This combination presents numerous challenges particularly for people with dementia, as the correct administration of the drugs can frequently no longer be guaranteed. The drug treatment of neuropsychiatric symptoms of dementia are often treated with antipsychotics with potentially severe side effects and with limited efficacy. Moreover, many drugs have an anticholinergic potential, which may worsen the cognitive function even further in patients with dementia. The use of anticholinergic drugs should be handled with care and when possible be avoided in patients with dementia.

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http://dx.doi.org/10.1007/s00108-023-01631-wDOI Listing

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