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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10697789 | PMC |
| http://dx.doi.org/10.1055/a-2208-5432 | DOI Listing |
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Background: CHRFAM7A is a human-restricted gene associated with neuropsychiatric and neurodegenerative disorders. The translated CHRFAM7A protein incorporates into the α7 nicotinic acetylcholine receptor (α7nAChR) leading to a hypomorphic receptor. Mechanistic insight from isogenic iPSC derived neuronal and mononuclear cells demonstrated that CHRFAM7A affects Ca signaling and activates small GTPase Rac1 leading to an actin cytoskeleton gain of function.
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Division of Anatomy, Meikai University School of Dentistry.
Background: The acini, the secretory endpieces of the salivary glands, are composed of serous and/or mucous acinar cells and surrounded by myoepithelial cells. Myoepithelial cells are multipolar, stellate cells with long processes encircling the acini and intercalated ducts. These cells contract to facilitate salivary secretion and transport.
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Centrosome amplification (CA), an abnormal increase in the number of centrosomes in the cell, is a recurrent phenomenon in lung and other malignancies. Although CA promotes tumor development and progression by inducing genomic instability (GIN), it also induces mitotic stress that jeopardizes cellular integrity. CA leads to the formation of multipolar mitotic spindles that can cause lethal chromosome segregation errors.
View Article and Find Full Text PDFFlexible Terahertz Metasurface Absorbers Empowered by Bound States in the Continuum.
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State Key Laboratory of Optical Fiber and Cable Manufacture Technology, Department of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, 518055, China.
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- Terahertz absorbers play a vital role in advanced wireless communications, imaging, sensing, and stealth technologies, significantly impacting detector performance and cloaking abilities.
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