Stem cell-based mammalian embryo models facilitate the discovery of developmental mechanisms because they are more amenable to genetic and epigenetic perturbations than natural embryos. Here, we highlight exciting recent advances that have yielded a plethora of models of embryonic development. Imperfections in these models highlight gaps in our current understanding and outline future research directions, ushering in an exciting new era for embryology.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556421 | PMC |
| http://dx.doi.org/10.1016/j.gde.2023.102134 | DOI Listing |
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A comparative study of human amniotic membrane, tilapia skin collagen, and Centella asiatica derived gel to treat burn wound in rat model.
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In the quest for an ideal wound healing material, human amniotic membrane (AM), tilapia skin collagen (TSC), and Centella asiatica (CA) have been studied separately for their healing potential. In this study, we formulated AM, TSC, and CA gel and studied their competency and wound healing efficacy in vivo. Gel was formulated using AM, TSC, CA, Carbopol 934, acrylic acid, glycerine, and triethanolamine and physicochemical properties e.
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Department of Chemistry, School of Physics, Chemistry and Earth Sciences, The University of Adelaide, Adelaide, South Australia, 5005, Australia. Electronic address:
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View Article and Find Full Text PDFHypoxic culture enhances the antimicrobial activity of amnion-derived mesenchymal stem cells, thereby reducing bacterial load and promoting wound healing in diabetic mice.
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Department of Plastic and Reconstructive Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan. Electronic address:
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View Article and Find Full Text PDFEpidermal Growth Factor Intralesional Delivery in Chronic Wounds: The Pioneer and Standalone Technique for Reversing Wound Chronicity and Promoting Sustainable Healing.
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Joseph E. Murray Professor of Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Harvard Medical School, Main Pike, ASB-2, 75 Francis St, Boston, MA 02115, USA.
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