The reduction of nitroarenes using KBH and I is described. BI is generated in situ and was shown to be the active reductant. Conditions were optimized for BI generation and then applied to a wide range of nitroarenes, including traditionally challenging substrates. The method constitutes a practical reduction option which produces low-toxicity boric acid and potassium iodide upon workup.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10729015 | PMC |
| http://dx.doi.org/10.1021/acs.orglett.3c03257 | DOI Listing |
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