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CNN-Based Cross-Modality Fusion for Enhanced Breast Cancer Detection Using Mammography and Ultrasound.
Tomography
December 2024
Department of Medical Imaging and Radiological Science, I-Shou University, Kaohsiung City 824005, Taiwan.
Breast cancer is a leading cause of mortality among women in Taiwan and globally. Non-invasive imaging methods, such as mammography and ultrasound, are critical for early detection, yet standalone modalities have limitations in regard to their diagnostic accuracy. This study aims to enhance breast cancer detection through a cross-modality fusion approach combining mammography and ultrasound imaging, using advanced convolutional neural network (CNN) architectures.
View Article and Find Full Text PDFPDGFR-α shRNA-polyplex for uveal melanoma treatment via EMT mediated vasculogenic mimicry interfering.
J Nanobiotechnology
December 2024
National Engineering Research Center of Ophthalmology and Optometry, School of Biomedical Engineering, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Up to 50% of individuals with uveal melanoma (UM), a frequent cancer of the eye, pass away from metastases. One of the major challenges in treating UM is the role of receptor tyrosine kinases (RTKs), which mediate the epithelial-mesenchymal transition (EMT) of tumors. RTKs are involved in binding multiple growth factors, leading to angiogenesis and vasculogenic mimicry (VM) phenomena.
View Article and Find Full Text PDFp53 and Ki-67 combined with periodic acid-Schiff staining for the diagnosis of early stage esophageal squamous cell carcinoma lesions in biopsy specimens.
Esophagus
December 2024
Department of Pathology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China.
Background: Esophageal cancer is highly prevalent in China, predominantly represented by squamous cell carcinoma. This retrospective study sought to evaluate the diagnostic efficacy of four staining protocols in identifying early stage esophageal squamous cell carcinoma (ESCC).
Methods: A consecutive series of ninety biopsy samples of esophageal mucosa, collected retrospectively from March 2016 to December 2019, were obtained at Beijing Chao-Yang Hospital, a tertiary care facility in Beijing, China.
Comparative analysis of clinical characteristics of symptomatic pituitary adenomas in elderly patients: a consecutive series of 114 patients.
Front Endocrinol (Lausanne)
December 2024
Department of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Background: Pituitary adenomas (PAs) present with clinical features such as neuroendocrine abnormalities and mass effects, common in the general morbidity population. However, in elderly patients, the disease progression renders some clinical features difficult to detect and identify in time. Consequently, elderly patients with PAs are often not identified and receive sufficient intervention on time to achieve a satisfactory outcome.
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Therapie
December 2024
VIM Suresnes, UMR_0892, hôpital Foch, université Paris-Saclay, 92150 Suresnes, France.
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