Targeted amplification-based whole genome sequencing of in clinical specimens.

Microbiol Spectr

Public Health Ontario Laboratory, Public Health Ontario , Toronto, Ontario, Canada.

Published: January 2024

We present a protocol to efficiently sequence genomes of the MPXV-causing mpox. This enables researchers and public health agencies to acquire high-quality genomic data using a rapid and cost-effective approach. Genomic data can be used to conduct surveillance and investigate mpox outbreaks. We present 91 mpox genomes that show the diversity of the 2022 mpox outbreak in Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10783113PMC
http://dx.doi.org/10.1128/spectrum.02979-23DOI Listing

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