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Leveraging digital health systems maturity assessments to guide strategic priorities.
J Public Health Afr
December 2024
Department of Global Health, University of Washington, Seattle, United States of America.
Background: Many low- and middle-income countries (LMICs) face the daunting task of digitising, maturing and deciding where to invest in digital health systems.
Aim: Describing the facilitators and barriers to conducting digital health maturity assessments and how health leaders can prioritise the assessments.
Setting: eHealth leaders from 10 African countries, working or supporting Ministries of Health's digital health and participating in the eHealth Leaders' Forum from July 2023 to September 2023.
Non-adherence to Clinical Practice Guidelines in Regional Anesthesia and Pain Interventions: Insights From a Comprehensive Case Series Review.
Cureus
December 2024
Clinical Pathology Department, Faculty of Medicine, Assiut University, Assiut, EGY.
Adhering to established guidelines, regional anesthesia (RA) and pain interventions are essential for preventing or minimizing the risk of complications. This study examines neurological complications that may arise when RA or pain interventions are performed without adherence to the clinical practice guidelines. This article aimed to emphasize the relationship between deviations from standards of care in RA and neurological outcomes.
View Article and Find Full Text PDFUsing Osteopathic Manipulative Therapy to Treat Irritable Bowel Syndrome and Severe Refractory Gastroesophageal Reflux Disease: A Case Report.
Cureus
December 2024
Department of Osteopathic Principles and Practice, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Tampa, USA.
Both Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD) pose significant healthcare burdens on the general population of America. Though first-line medications are available, concomitant burdens of polypharmacy, side effects, and inadequate control exist. Osteopathic Manipulative Treatment (OMT) is a hands-on, physical manipulation technique that offers a personalized and direct approach to modifying the body's neuromuscular and viscerosomatic activity leading to decreased symptomatic burden with minimal side effects.
View Article and Find Full Text PDFOnce-weekly IcoSema versus once-weekly semaglutide in adults with type 2 diabetes: the COMBINE 2 randomised clinical trial.
Diabetologia
January 2025
Internal Medicine Department, Endocrine Division (SEMPR), Universidade Federal do Paraná, Curitiba, Brazil.
Aims/hypothesis: COMBINE 2 assessed the efficacy and safety of once-weekly IcoSema (a combination therapy of basal insulin icodec and semaglutide) vs once-weekly semaglutide (a glucagon-like peptide-1 analogue) 1.0 mg in individuals with type 2 diabetes inadequately managed with GLP-1 receptor agonist (GLP-1 RA) therapy, with or without additional oral glucose-lowering medications.
Methods: This 52 week, randomised, multicentre, open-label, parallel group, Phase IIIa trial was conducted across 121 sites in 13 countries/regions.
Inadequate awareness and attention to non-HDL cholesterol: undertreatment of high-risk patients in cardiology practice in Turkey.
Coron Artery Dis
January 2025
Department of Cardiology, Faculty of Medicine, Ege University, Izmir, Turkey.
Background: The relationship between low-density lipoprotein cholesterol (LDL-C) and atherosclerotic cardiovascular disease (ASCVD) is well-established. Recently, non-high-density lipoprotein cholesterol (non-HDL-C) has been validated as a superior predictor of ASCVD, especially in individuals with mild to moderate hypertriglyceridemia. The EPHESUS study evaluated real-life hypercholesterolemia management and awareness of non-HDL-C in cardiology outpatient practices.
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