Introduction: The extravascular implantable cardioverter defibrillator (EV ICD) has extended projected battery longevity compared to the subcutaneous implantable cardioverter defibrillator (S-ICD). This study used modeling to characterize the need for generator changes, long-term complications, and overall costs for both the EV ICD and S-ICD in healthcare systems of various countries.
Methods: Battery longevity data were modeled using a Markov model from averages reported in device labeling for the S-ICD and with engineering estimates based on real life usage from EV ICD Pivotal Study patient data to introduce variability. Clinical demographic data were derived from published literature. The primary outcomes were defined as the number of generator replacement surgeries, complications, and total healthcare system costs due to battery depletion over the expected lifetime of patients receiving EV ICD or S-ICD therapy.
Results: Average modeled battery longevity was determined to be 7.3 years for the S-ICD versus 11.8 years for the EV ICD. The probability of a complication after a replacement procedure was 1.4%, with an operative mortality rate of 0.02%. The use of EV ICD was associated with 1.4-1.6 fewer replacements on average over an expected patient lifetime as compared to S-ICD and a 24.3%-26.0% reduction in cost. A one-way sensitivity analysis of the model for the US healthcare system found that use of an EV ICD resulted in a reduction in replacement surgeries of greater than 1 (1.1-1.6) along with five-figure cost savings in all scenarios ($18 602-$40 948).
Conclusion: The longer projected battery life of the EV ICD has the potential to meaningfully reduce long-term morbidity and healthcare resources related to generator changes from the perspective of multiple diverse healthcare systems.
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http://dx.doi.org/10.1111/jce.16150 | DOI Listing |
Microsyst Nanoeng
December 2024
Department of Computer and Information Engineering, Khalifa University, Abu Dhabi, 12778, UAE.
The demand for sustainable energy sources to power small electronics like IoT devices has led to exploring innovative solutions like acoustic energy harvesting using piezoelectric nanogenerators (PENGs). Acoustic energy harvesting leverages ambient noise, converting it into electrical energy through the piezoelectric effect, where certain materials generate an electric charge in response to mechanical stress or vibrations. This review paper provides a comprehensive analysis of the advancements in PENG technology, emphasizing their role in acoustic energy harvesting.
View Article and Find Full Text PDFNeurosurgery
December 2024
Department of Neurosurgery, University of Arizona College of Medicine, Tucson, Arizona, USA.
Background And Objectives: Patients undergoing thalamic ventral intermediate nucleus stimulation to treat essential tremor (ET) develop tolerance over time, requiring higher stimulation amplitudes that lead to more frequent battery changes and suboptimal tremor control. The study objective is to determine whether amplitude tolerance differs between patients with omnidirectional vs directional leads.
Methods: We conducted a retrospective analysis of ET patients with omnidirectional and directional leads implanted between 2005 and 2022.
Phys Chem Chem Phys
December 2024
Institute for Physical Chemistry, University of Münster, Münster, Germany.
As the demand for high-energy batteries to power electric vehicles continues to grow, Ni-rich cathode materials have emerged as promising candidates due to their high capacity. However, these materials are prone to rapid degradation under increased voltages, posing significant challenges for their long-term stability and safety. In this study, we investigate the effects of tantalum (Ta) doping on the performance and stability of LiNiMnCoO (NMC811) cathode materials.
View Article and Find Full Text PDFHeart Rhythm O2
November 2024
Boston Scientific, Marlborough, MA.
Background: Cardiac resynchronization therapy-defibrillators (CRT-D) are devices established as treatment for symptomatic heart failure patients at risk of sudden cardiac death. Battery depletion poses a significant clinical and economic burden; extended service life may reduce costs because of generator changes and associated complications.
Objective: This study estimated cost-savings associated with extended battery longevity in Medicare patients receiving CRT-D implantation.
Sci Rep
November 2024
Associate Professor, Department of Electrical and Electronics Engineering, Vignan Foundation for Science Technology & Research, Guntur, 522017, India.
The design and construction of an adaptive energy management system incorporating a 12 V-2 Ah battery and a 1F ultracapacitor for solar powered hybrid electric vehicles are presented in this paper. The primary storage battery's longevity and overall system efficiency are intended to be increased by the EMS's ability to forecast driving circumstances and lessen the load on it. The method optimizes power distribution among numerous energy storage sources by using sophisticated hardware configurations.
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