Six-month outcomes following venovenous ECMO for severe COVID-19 and viral pneumonitis: 2019-2020 Australian experience.

Crit Care Resusc

Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

Published: March 2022

AI Article Synopsis

  • The study compares COVID-19 patients and non-COVID-19 viral pneumonitis patients receiving VV-ECMO in seven Australian ICUs, focusing on their characteristics, treatment, and 6-month outcomes.
  • Patients with COVID-19 were generally older, experienced a longer time from intubation to ECMO, but had comparable illness severity scores to those with other viral pneumonitis.
  • Despite similar functional outcomes and mortality rates after six months, COVID-19 patients had significantly longer ICU and hospital stays, suggesting potential resource challenges for healthcare systems.

Article Abstract

To compare the characteristics, treatments and 6-month functional outcomes of patients with coronavirus disease 2019 (COVID-19) versus non-COVID-19 viral pneumonitis supported by venovenous extracorporeal membrane oxygenation (VV-ECMO). Prospective, observational cohort study in seven intensive care units (ICUs) across Australia. Patients admitted to participating ICUs with laboratory-confirmed COVID-19 or viral pneumonitis requiring VV-ECMO. From 30 March 2019 to 31 December 2020, 13 patients were initiated on VV-ECMO for COVID-19 and 23 were initiated for non-COVID-19 viral pneumonitis. Patients with COVID-19 were older and had a longer duration from intubation to ECMO initiation, but had similar illness severity and APACHE IV scores at the time of initiation. Overall disability, health-related quality of life, and mortality were similar, but ICU and hospital length of stay were significantly longer in patients with COVID-19. Six-month functional outcomes and mortality were similar between COVID-19 and viral pneumonitis patients treated with VV-ECMO. However, length of stay was longer in COVID-19 patients, which may have resource implications.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692629PMC
http://dx.doi.org/10.51893/2022.1.OA10DOI Listing

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