Background And Objective: For several years, there has been growing concern over the public and animal health impacts of dog importation, with many Canadian veterinarians reporting increasing diagnoses of exotic pests and pathogens. This study is the first to estimate the number of dogs imported into Canada and describe spatial and temporal trends.
Animal And Procedure: Commercial and a subset of personal dog importation records, obtained from the Canada Border Services Agency, were used to estimate the total number of dogs imported into Canada from 2013 to 2019.
Results: The number of dogs imported annually increased by > 400% over the study period, with > 37 000 dogs imported in 2019. The majority of dogs (72%) were imported from the United States and Eastern Europe, and 23% originated in a country considered high-risk for canine rabies.
Conclusion: Dog importation into Canada has increased substantially over time. Moving forward, education and improved tracking will be essential.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637708 | PMC |
Microorganisms
January 2025
WOAH Reference Laboratory for Brucellosis, Department of Brucellosis Research, Agricultural Research Center, Animal Health Research Institute, P.O. Box 264-Giza, Cairo 12618, Egypt.
Brucellosis is a neglected zoonotic disease that has a significant economic and public health impact, especially in endemic countries. This review delves deeply into brucellosis's current epidemiological situation and potential sources of livestock infection in Egypt during the last two decades. MLVA-16 and Whole Genome Sequencing based on core-genome SNP analyses confirm the presence of different and outbreak strains, both older widely disseminated strains and newly introduced ones.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Engineering Research Center of Key Technology and Industrialization of Cell-Based Vaccine, Ministry of Education, Lanzhou 730030, China.
Madin-Darby Canine Kidney (MDCK) cells are a key cell line for influenza vaccine production, due to their high viral yield and low mutation resistance. In our laboratory, we established a tertiary cell bank (called M60) using a standard MDCK cell line imported from American Type Culture Collection (ATCC) in the USA. Due to their controversial tumourigenicity, we domesticated non-tumourigenic MDCK cells (named CL23) for influenza vaccine production via monoclonal screening in the early stage of this study, and the screened CL23 cells were characterised based on their low proliferative capacity, which had certain limitations in terms of expanding their production during cell resuscitation.
View Article and Find Full Text PDFCan Vet J
January 2025
Department of Population Medicine (Belanger, Spence, Clow) and Department of Pathobiology (Weese), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1; Ontario Ministry of Agriculture, Food and Agribusiness, 1 Stone Road West, Guelph, Ontario N1G 4Y2 (Anderson).
Background: As numbers of dogs entering Canada from abroad are increasing, it is essential to understand the scope, challenges, and risks associated with canine importation. Canadian veterinarians' collective experience with and clinical knowledge of imported dogs can provide valuable insights into this practice.
Objective: To describe Canadian veterinarians' experiences with, and perspectives of, imported dogs in clinical practice.
Pathogens
December 2024
Institute of Microbiology, Department for Environment Constructions and Design, University of Applied Sciences and Arts of Southern Switzerland (SUPSI), 6850 Mendrisio, Switzerland.
Although Switzerland is currently not endemic for canine leishmaniosis (CanL), imported cases of this emerging zoonosis are regularly detected. Also, phlebotomine sand flies, vectors of the causative agent , are present in the southern part of the country, in Canton Ticino, and endemic foci of CanL have been recently described in neighboring Italian municipalities. In 2022 and 2023, we evaluated the distribution of phlebotomine sand flies and the presence of antibodies against in domestic dogs and cats in Ticino and Mesolcina (Canton of Grisons).
View Article and Find Full Text PDFMob DNA
January 2025
Department of Biology, La Sierra University, Riverside, CA, USA.
Background: Messenger RNA 3' untranslated regions (3'UTRs) control many aspects of gene expression and determine where the transcript will terminate. The polyadenylation signal (PAS) AAUAAA (AATAAA in DNA) is a key regulator of transcript termination and this hexamer, or a similar sequence, is very frequently found within 30 bp of 3'UTR ends. Short interspersed element (SINE) retrotransposons are found throughout genomes in high copy numbers.
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