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Respiratory syncytial virus vaccination in older adults and patients with chronic disorders: A position paper from the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine.
Pulmonology
December 2025
Portuguese Society of Pulmonology (SPP), Lisbon, Portugal.
Background: Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection, hospitalisation and death in adults.
Methods: Based on evidence regarding the impact of RSV on adult populations at risk for severe infection and the efficacy and safety of RSV vaccines, the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine endorses this position paper with recommendations to prevent RSV-associated disease and its complications in adults through vaccination.
Conclusion: The RSV vaccine is recommended for people aged ≥50 years with risk factors (chronic obstructive pulmonary disease, asthma, heart failure, coronary artery disease, diabetes, chronic kidney disease, chronic liver disease, immunocompromise, frailty, dementia, and residence in a nursing home) and all persons aged ≥60 years.
Poor Oral Health-Related Quality of Life and Frailty Among PLWHIV: A Cross-Sectional Study.
J Int Soc Prev Community Dent
December 2024
Faculty of Medicine, Federal University of Bahia, Salvador, Bahia, Brazil.
Aims: This study aimed to explore the association between frailty and pre-frailty in people living with human immunodeficiency virus (PLWHIV), focusing on their oral health-related quality of life (OHRQoL) and health-related quality of life (HRQoL).
Materials And Methods: A cross-sectional study was conducted with 184 PLWHIV. Frailty status was assessed using Fried's frailty criteria, categorizing participants as robust, pre-frail, or frail.
Impact of frailty and comorbidity on initial response to lung cancer screening invitation and low-dose CT screening uptake: Findings from the Yorkshire Lung Screening Trial.
J Med Screen
January 2025
Leeds Institute of Health Sciences, School of Medicine, University of Leeds, Leeds, UK.
Background: Low-dose computed tomography screening reduces lung cancer-specific mortality in high-risk individuals. Lung cancer risk factors overlap with comorbid diseases, highlighting the significance of frailty and comorbidities for lung cancer screening (LCS). Here, we describe the prevalence of frailty and comorbidity in those invited for LCS and evaluate their associations with response to telephone risk assessment invitation and subsequent uptake of LCS.
View Article and Find Full Text PDFRecurrent events modeling based on a reflected Brownian motion with application to hypoglycemia.
Biostatistics
December 2024
Department of Statistics, University of Connecticut, 215 Glenbrook Road Unit 4120, Storrs, CT 06269, United States.
Patients with type 2 diabetes need to closely monitor blood sugar levels as their routine diabetes self-management. Although many treatment agents aim to tightly control blood sugar, hypoglycemia often stands as an adverse event. In practice, patients can observe hypoglycemic events more easily than hyperglycemic events due to the perception of neurogenic symptoms.
View Article and Find Full Text PDFFrailty and social contact with dementia risk: A prospective cohort study.
J Affect Disord
January 2025
Department of Neurology & Innovation Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, China; National Center for Neurological Disorders, Xuanwu Hospital, Capital Medical University, Beijing, China; Neurodegenerative Laboratory of Ministry of Education of the People's Republic of China, Beijing, China. Electronic address:
Background: Frailty and social contact are significant factors influencing dementia risk. While previous studies have separately examined these factors, their combined impact on dementia remains underexplored.
Methods: This study included 338,567 UK biobank participants from 2006 to 2010, with follow-up until December 2022.
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