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[A CASE OF CASHEW NUT-RELATED CITRUS SEED ALLERGY WITH SUSPECTED CITRIN INVOLVEMENT].
Arerugi
November 2024
Department of Pediatrics, Jichi Medical University Saitama Medical Center.
The case is a 12-year-old girl. She was diagnosed with cashew nut allergy in infancy. She experienced the following allergic symptoms at age 11: sore throat after ingesting gummy bears containing citrus-derived pectin; sore throat, nausea, and severe abdominal pain after ingesting jelly containing yuzu (citrus junos) seeds and peel.
View Article and Find Full Text PDFCitrin allergy is rare but perplexing.
Ann Allergy Asthma Immunol
December 2023
Section of Pediatric Allergy & Immunology, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado. Electronic address:
Citrin: a novel food allergen in citrus seeds and citrus-derived pectin that shows cross-reactivity with cashew and pistachio.
Ann Allergy Asthma Immunol
December 2023
NYU Grossman School of Medicine, Allergy and Immunology, Hassenfeld Children's Hospital, New York, New York; Department of Pediatrics, Gastroenterology and Nutrition, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Background: Patients exquisitely sensitive to cashew/pistachio are at risk for allergic reactions to citrus seeds and pectin.
Objective: In this study, we sought to evaluate whether pectin is contaminated with citrus seeds, to identify a culprit antigen in citrus seeds, and to assess for cross-reactivity among allergens in citrus seeds, citrus pectin, and cashew or pistachio.
Methods: Proteins from orange seed coats, orange seed endosperms, lemon seeds, grapefruit seeds, citrus pectin, apple pectin, and grapefruit pectin were extracted.
Clinical findings in five Turkish patients with citrin deficiency and identification of a novel mutation on SLC25A13.
J Pediatr Endocrinol Metab
January 2020
Behçet Uz Children Training and Research Hospital, Pediatric Allergy and Immunology Department, Izmir, Istanbul, Turkey.
Background Citrin deficiency (CD) is an autosomal recessive genetic disorder caused by a defect in the mitochondrial aspartate/glutamate antiporter, citrin. Three clinical manifestations have been described until today. Case presentation We reported 5 CD patients from two families.
View Article and Find Full Text PDFRadiation-Induced Fibrosis: Mechanisms and Opportunities to Mitigate. Report of an NCI Workshop, September 19, 2016.
Radiat Res
July 2017
b Radiation Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
A workshop entitled "Radiation-Induced Fibrosis: Mechanisms and Opportunities to Mitigate" (held in Rockville, MD, September 19, 2016) was organized by the Radiation Research Program and Radiation Oncology Branch of the Center for Cancer Research (CCR) of the National Cancer Institute (NCI), to identify critical research areas and directions that will advance the understanding of radiation-induced fibrosis (RIF) and accelerate the development of strategies to mitigate or treat it. Experts in radiation biology, radiation oncology and related fields met to identify and prioritize the key areas for future research and clinical translation. The consensus was that several known and newly identified targets can prevent or mitigate RIF in pre-clinical models.
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