AI Article Synopsis
- * An isolation rate of 15.8% was found, with the majority of recovered strains being serotype 31, indicating a significant prevalence of this particular strain.
- * The research identified 90.7% of isolates carrying virulence-associated genes and discovered 70 novel sequence types, some of which showed genetic similarities to strains from Spain and the USA, enhancing the understanding of S. suis in the country.
Article Abstract
This study aimed to determine the presence and characteristics of locally circulating strains of Streptococcus suis, the most important streptococcal pathogen in swine. Oral swab samples were collected from pigs from 664 representative smallhold farms across nine provinces in the Philippines. Isolates were identified and characterized using PCR assays. The study revealed an isolation rate of 15.8% (105/664, 95% CI: 13.0-18.6) among the sampled farms. Two hundred sixty-nine (269) S. suis isolates were recovered from 119 unique samples. Serotype 31 was the most prevalent (50/269, 95% CI: 13.9-23.2) among the other serotypes identified: 5, 6, 8, 9, 10, 11, 15, 16, 17, 21, 27, 28, and 29. The detection of the three 'classical' S. suis virulence-associated genes showed that 90.7% (244/269, 95% CI: 87.2-94.2) were mrp/epf/sly Multilocus sequence typing (MLST) analysis further revealed 70 novel sequence types (STs). Notably, several local isolates belonging to these novel STs formed clonal complexes (CC) with S. suis strains recovered from Spain and USA, which are major pork-exporting countries to the Philippines. This study functionally marks the national baseline knowledge of S. suis in Philippines.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10692119 | PMC |
| http://dx.doi.org/10.1038/s41598-023-48406-9 | DOI Listing |
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