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SUMOylation of TRIM28 is positively modulated by the BTB/POZ domain of Kaiso.
Mol Biol Rep
January 2025
Federal Research Centre «Fundamentals of Biotechnology», Russian Academy of Sciences, Moscow, Russia, 119071.
Background: TRIM28 plays a crucial role in maintaining genomic stability and establishing imprinting, facilitated by the diversity of KRAB zinc finger proteins. The SUMOylation of TRIM28 is essential for its function and is enhanced in the presence of the KRAB domain. Previously, we demonstrated that Kaiso, another factor capable of interacting with TRIM28, can promote its SUMOylation.
View Article and Find Full Text PDFIn vitro evaluation of silver-zinc oxide-eugenol nanocomposite for enhanced antimicrobial and wound healing applications in diabetic conditions.
Discov Nano
January 2025
Department of Biotechnology, Alagappa University, Karaikudi, 630003, India.
Diabetic wounds with chronic infections present a significant challenge, exacerbated by the growing issue of antimicrobial resistance, which often leads to delayed healing and increased morbidity. This study introduces a novel silver-zinc oxide-eugenol (Ag+ZnO+EU) nanocomposite, specifically designed to enhance antimicrobial activity and promote wound healing. The nanocomposite was thoroughly characterized using advanced analytical techniques, confirming its nanoscale structure, stability and chemical composition.
View Article and Find Full Text PDFNanoengineered RF-Sputtered MnO Cathode Thin Films for Aqueous Zinc-Ion Batteries: Insights into Diffusion Dynamics and Application Potential.
J Phys Chem Lett
January 2025
Thin film Energy Storage Laboratory, Department of Physics and Nanotechnology, SRM Institute of Science and Technology, Kattankulathur 603 203Tamil Nadu India.
Manganese oxides are a promising cathode material for aqueous zinc-ion batteries (AZIBs), but thin-film configurations remain underexplored. This study investigates the electrochemical dynamics of 60 nm thin MnO thin films, fabricated via RF magnetron reactive sputtering. It addresses the highest reported capacity (25 mAh/g) in thin film form, stability over 500 cycles, effective performance across varying current rates, surpassing previous studies and challenges such as phase stability, and capacity fading over extended cycling, aiming to enhance uniformity, minimizing diffusion barriers for improved performance.
View Article and Find Full Text PDFEffect of zinc level and the thermal environment on the zootechnical performance and tibia-breaking strength of Japanese quails.
Front Vet Sci
January 2025
Research Group in Bioclimatology, Ethology and Animal Welfare (BioEt), Department of Animal Science, Federal University of Paraiba, Areia, Paraiba, Brazil.
Japanese quails () are sensitive to zinc (Zn) deficiency, a mineral essential for growth, development, and bone health. This study evaluated the effects of different levels of Zn in the diet on zootechnical performance, organ and carcass weight, and tibial breakage resistance in quails from 1 to 42 days of age. A 5 × 2 factorial design was used, consisting of five Zn levels (30, 60, 90, 120, and 150 mg/kg) and two thermal environments (thermal comfort and heat stress), with five replicates of 10 birds per treatment.
View Article and Find Full Text PDFComposite dietary antioxidant index is inversely and nonlinearly associated with cardiovascular disease, atherosclerotic cardiovascular disease, and cardiovascular mortality in people with dyslipidemia: evidence from NHANES 2001-2018.
Front Nutr
January 2025
Department of Critical Care Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Background: Dyslipidemia is a major risk factor for cardiovascular disease (CVD) and atherosclerotic CVD (ASCVD). The composite dietary antioxidant index (CDAI), an emerging measure of combined dietary antioxidant exposure, may provide insights into the relationship between diet and CVD/ASCVD outcomes. We aimed to explore the association between CDAI and the prevalence of CVD/ASCVD, as well as CVD mortality in individuals with dyslipidemia.
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