Acquired digital fibrokeratoma is a rare, benign tumor that mostly occurs on the fingers and toes and may appear to be a supernumerary rudimentary digit. It generally affects adult men and appears as a dome-shaped papule although it can also be elongated or pedunculated. Trauma is believed to be a triggering factor in some cases. We report a male patient with an acquired digital fibrokeratoma on a finger, shaped like a cutaneous horn, and a history of minimal repeated trauma and spontaneous remissions not previously described in the literature.
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http://dx.doi.org/10.7759/cureus.47997 | DOI Listing |
Asia Ocean J Nucl Med Biol
January 2025
Department of Radiology, Faculty of Medicine, Shimane University, Izumo, Japan.
Objectives: We investigated image quality and standardized uptake values (SUVs) for different lesion sizes using clinical data generated by F-FDG-prone breast silicon photomultiplier (SiPM)-based positron emission tomography/computed tomography (PET/CT).
Methods: We evaluated the effect of point-spread function (PSF) modeling and Gaussian filtering (Gau) and determined the optimal reconstruction conditions. We compared the signal-to-noise ratio (SNR), contrast, %coefficient of variation (%CV), SUV, and Likert scale score between ordered-subset expectation maximization (OSEM) time-of-flight (TOF) and OSEM+TOF+PSF in phantom and clinical studies.
Br J Oral Maxillofac Surg
November 2024
Department of Oral and Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies/USP (HRAC/USP), Bauru, Sao Paulo, Brazil.
This study aims to evaluate the post-surgical stability of patients with cleft lip and palate that underwent maxillary advancement surgery. The study was conducted by means of cephalometric analysis of the soft tissues in digital radiographs acquired preoperatively, immediate postoperatively and six months after surgery using Dolphin Imaging 11.5 software.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109.
Life at all scales is surprisingly effective at exploiting new opportunities, as demonstrated by the rapid emergence of antimicrobial resistance and novel pathogens. How populations acquire this level of evolvability and the various ways it aids survival are major open questions with direct implications for human health. Here, we use digital evolution to show that changing environments facilitate the simultaneous evolution of high mutation rates and a distribution of mutational effects skewed toward beneficial phenotypes.
View Article and Find Full Text PDFJ Vet Intern Med
December 2024
Davies Veterinary Specialists, Part of Linnaeus Veterinary Limited, Hitchin, UK.
Background: Approximately 80% of nasal masses in dogs and 91% of nasal masses in cats are reported to be malignant, but the currently reported diagnostic rate of neoplasia is 54% using blind or rhinoscopic biopsy techniques.
Hypothesis/objectives: Describe the technique of computed tomography (CT)-guided Tru-Cut (Tru-Cut biopsy needle, Merit Medical Systems, Utah, USA) nasal biopsies in cats and dogs to determine the diagnostic rate of neoplasia on the first round of sampling and to evaluate the safety of the technique.
Animals: Thirty client-owned animals, 16 dogs and 14 cats, that had CT-guided nasal biopsies performed to investigate nasal masses.
Netw Neurosci
December 2024
Retired Professor, The University of Melbourne, Victoria, Australia.
Several recent studies have optimized deep neural networks to learn high-dimensional relationships linking structural and functional connectivity across the human connectome. However, the extent to which these models recapitulate individual-specific characteristics of resting-state functional brain networks remains unclear. A core concern relates to whether current individual predictions outperform simple benchmarks such as group averages and null conditions.
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