Endometrial osseous metaplasia (EOM) is an uncommon clinical entity with the presence of bone in the endometrium which requires clinical and therapeutic framework. It is also described by various other names such as endometrial ossification, ectopic intrauterine bone, and heterotopic intrauterine bone. Ossification could have various locations as the cervix the ovary, and the vagina. This overview highlights the attention on the actual pivotal points of EOM.
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http://dx.doi.org/10.4103/gmit.gmit_89_22 | DOI Listing |
Geriatrics (Basel)
December 2024
Klinik für Herzchirurgie, Klinikum Nürnberg-Paracelsus Medical University, 90471 Nuremberg, Germany.
We report the case of a 78-year-old female patient who received palliative immunotherapy with pembrolizumab and lenvatinib as a treatment of pulmonary and osseous metastatic endometrial carcinoma. Under this therapy, the patient developed dysphagia, thyroiditis with hypothyroidism, myositis, and myocarditis, which required, due to third-degree AV block, the installation of a pacemaker. The patient received high-dose cortisone therapy, a thyroid hormone substitution, and pyridostigmine for symptom control.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Division of Gynecology and Obstetrics, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Background: Subtle uterine lesions are abnormal intracavitary conditions that, while not causing significant anatomical changes, can adversely impact fertility. Identifying these "subtle" lesions is challenging due to arbitrary interpretation, varied management strategies, unclear clinical significance, and insufficient clinician training in recognizing them. Hysteroscopy offers direct visualization and the capacity to obtain targeted biopsies, making it an invaluable tool for the diagnosis and treatment of these often overlooked conditions.
View Article and Find Full Text PDFBMJ Case Rep
December 2024
Obstetrics and Gynecology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Osseous metaplasia of the endometrium is a rare condition involving the bone tissue in the endometrial cavity. Its presence along with haematometra is an infrequent condition and is not reported until now. We present a case of a woman in her mid-30s with primary infertility and secondary amenorrhoea.
View Article and Find Full Text PDFMost bone tumors are metastatic. Breasts, lungs, kidneys, and thyroid are the primary sites most commonly involved in bone metastasis-type outcomes. This case study describes the involvement of a patient with a bone tumor located in the axial skeleton, initially in the sacral region.
View Article and Find Full Text PDFInt J Gynecol Cancer
August 2024
Hospital Universitario de Navarra, Pamplona, Spain.
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