Pleomorphic adenoma (PA) is a commonly occurring benign salivary gland tumour known for its surfeit of histo-morphologic appearances ranging from myxochondroid, plasmacytoid, and squamoid elements to the infrequently seen osseous and adipose tissue metaplasia. Oncocytic metaplastic changes, a rare finding, present in the form of sheets/islands/cords of polygonal cells with rich eosinophilic or occasionally clear cytoplasm and an oval/round nucleus. We report one such rare case which portrayed extensive oncocytic changes in a unique bilayered/multi-layered epithelium, lining the papillary cystic areas similar to that of Warthin's tumour and extensive keratinisation simulating the newly recognised entity "adnexa-like differentiation/trichilemmal keratinisation", along with foci of cholesterol clefts and multi-nucleated giant cells.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683888 | PMC |
http://dx.doi.org/10.4103/jomfp.jomfp_37_23 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!