AI Article Synopsis
- Scientists synthesized twenty oxygenated aristolochene compounds by integrating genes from four different fungal pathways into a fungal host.
- Among the compounds created was hypoxylan A and an epimer of guignaderemophilane C in a single step.
- A new fungal aromatase was identified, which generates phenols through a process called oxidative demethylation.
Article Abstract
Twenty oxygenated aristolochene congeners were rapidly synthesised by combining genes from four different fungal pathways in the fungal host organism . Compounds produced in a single step include the natural product hypoxylan A and an epimer of guignaderemophilane C. A new fungal aromatase was discovered that produces phenols by oxidative demethylation.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686045 | PMC |
| http://dx.doi.org/10.1039/d3sc04172g | DOI Listing |
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