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Preparation of sodium hyaluronate coated liposomes: effect of polymer molecular weight, coating concentration, amount of charged lipids and type of hydration medium on the stability.
J Liposome Res
January 2025
SiteDel Group, Department of Pharmacy, University of Oslo, Blindern, Oslo, Norway.
In this study, liposomes consisting of soybean phosphatidyl choline (SoyPC) and different molar concentrations (10 mol% and 20 mol%) of dioleoyl trimethylammoniumpropane (DOTAP) were prepared by the thin film hydration method and coated with sodium hyaluronate (NaHA) of different MWs (8-15 kDa, 30-50 kDa and 90-130 kDa) and concentrations (0.01-0.2% w/w) using phosphate buffer (PB) or glycerol phosphate buffer (G-PB) as the hydration medium.
View Article and Find Full Text PDFRetinal OCT image classification based on MGR-GAN.
Med Biol Eng Comput
January 2025
School of Automation and Information Engineering, Sichuan University of Science & Engineering, Key Laboratory of Artificial Intelligence, Yibin, 644000, Sichuan, China.
Accurately classifying optical coherence tomography (OCT) images is essential for diagnosing and treating ophthalmic diseases. This paper introduces a novel generative adversarial network framework called MGR-GAN. The masked image modeling (MIM) method is integrated into the GAN model's generator, enhancing its ability to synthesize more realistic images by reconstructing them based on unmasked patches.
View Article and Find Full Text PDFApproaches for the preparation and evaluation of hydrophilic polyethylene and polyethylene terephthalate microplastic particles suited for toxicological effect studies.
Anal Bioanal Chem
January 2025
European Commission, Joint Research Centre (JRC), Geel, Belgium.
When performing effect studies to investigate the impact of microplastic (MP) on cell lines, algae, or daphnia, it is advantageous if such experiments can be performed without the use of surfactants. The need for surfactants arises from the fact that finely milled pristine MP particles generally are hydrophobic. Methods for the preparation of larger amounts of hydrophilic and hence artificially aged MP particles and approaches for their characterization are of high importance.
View Article and Find Full Text PDFPredictors of functional recovery following surgical repair of quadriceps tendon rupture: insights from a German multicentre study.
Arch Orthop Trauma Surg
January 2025
Training Center for Emergency Medicine (NOTIS E.V), Engen, Germany.
Introduction: More extensive and cohesive studies on quadriceps tendon rupture (QTR) repair surgery are required to guide effective treatment strategies. Therefore, in this study, we aimed to identify predictors of subjective functional recovery following QTR repair surgery.
Materials And Methods: This multicentre retrospective cohort study enrolled 191 adults (age ≥ 18 years) who underwent surgical unilateral QTR repair (2010-2022) and had ≥ 1-year postoperative follow-up at three trauma centres in Germany.
Neural Correlates of Social Touch Processing: An fMRI Study on Brain Functional Connectivity.
J Integr Neurosci
January 2025
Laboratory for the Study of Tactile Communication, Pushkin State Russian Language Institute, 117485 Moscow, Russia.
Background: The significance of tactile stimulation in human social development and personal interaction is well documented; however, the underlying cerebral processes remain under-researched. This study employed functional magnetic resonance imaging (fMRI) to investigate the neural correlates of social touch processing, with a particular focus on the functional connectivity associated with the aftereffects of touch.
Methods: A total of 27 experimental subjects were recruited for the study, all of whom underwent a 5-minute calf and foot massage prior to undergoing resting-state fMRI.
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