When evaluating the effect of carbon dioxide (CO) changes on Earth's climate, it is widely assumed that instantaneous radiative forcing from a doubling of a given CO concentration (IRF) is constant and that variances in climate sensitivity arise from differences in radiative feedbacks or dependence of these feedbacks on the climatological base state. Here, we show that the IRF is not constant, but rather depends on the climatological base state, increasing by about 25% for every doubling of CO, and has increased by about 10% since the preindustrial era primarily due to the cooling within the upper stratosphere, implying a proportionate increase in climate sensitivity. This base-state dependence also explains about half of the intermodel spread in IRF, a problem that has persisted among climate models for nearly three decades.
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http://dx.doi.org/10.1126/science.abq6872 | DOI Listing |
J Therm Biol
December 2024
NTU Psychology, Nottingham Trent University, Nottingham, NG1 4FQ, United Kingdom; Brain Function Research Group, School of Physiology, Faculty of Health Science, University of the Witwatersrand, South Africa.
As opportunistic generalists occupying a range of ecological niches, chacma baboons (Papio ursinus) are considered a highly flexible species of relatively low conservation priority. Underlying their ecological flexibility is a repertoire of behavioral strategies observed in response to ecological stressors. Although these strategies are relatively well-documented, we know very little about how they impact upon an individual's thermal and energetic physiology, which can influence population-level reproductive potential in the face of climatic warming.
View Article and Find Full Text PDFEnviron Toxicol Chem
January 2025
School of Environmental Science, University of Guelph, Guelph, ON, Canada.
Although not assessed in standard ecotoxicological tests, exposure to a toxicant that does not result in an observable adverse effect in the parents may lead to transgenerational effects. These are adverse effects observed in unexposed offspring as a result of their parents' exposure to a toxicant. The goal of this study was to investigate whether transgenerational effects are observed in freshwater snails exposed to a toxicant.
View Article and Find Full Text PDFBMJ
December 2024
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02120, USA.
Objective: To compare the effectiveness and safety of budesonide-glycopyrrolate-formoterol, a twice daily metered dose inhaler, and fluticasone-umeclidinium-vilanterol, a once daily dry powder inhaler, in patients with chronic obstructive pulmonary disease (COPD) treated in routine clinical practice.
Design: New user cohort study.
Setting: Longitudinal commercial US claims data.
Sensors (Basel)
December 2024
Intelligent Embedded Systems of Computer Science, University of Duisburg-Essen, 47057 Duisburg, Germany.
This study presents a comprehensive workflow for developing and deploying Multi-Layer Perceptron (MLP)-based soft sensors on embedded FPGAs, addressing diverse deployment objectives. The proposed workflow extends our prior research by introducing greater model adaptability. It supports various configurations-spanning layer counts, neuron counts, and quantization bitwidths-to accommodate the constraints and capabilities of different FPGA platforms.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Department of Integrated Biological Science, Pusan National University, Busan 46241, Republic of Korea.
For plant diseases to become established, plant pathogens require not only virulence factors and susceptible hosts, but also optimal environmental conditions. The accumulation of high soil salinity can have serious impacts on agro-biological ecosystems. However, the interactions between plant pathogens and salinity have not been fully characterized.
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