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http://dx.doi.org/10.1002/jhm.13238 | DOI Listing |
J Hosp Med
April 2024
Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
J Cereb Blood Flow Metab
September 2023
Cerebral Haemodynamics in Ageing and Stroke Medicine Group, Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Transfer function analysis (TFA) is the most frequently adopted method for assessing dynamic cerebral autoregulation (CA) with continuously recorded arterial blood pressure (ABP) and cerebral blood flow velocity (CBFV). Conventionally, values of autoregulatory metrics (e.g.
View Article and Find Full Text PDFNutr Clin Pract
April 2021
Division of Gastroenterology, Hepatology, and Nutrition, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Clinicians have widely recognized that indirect calorimetry (IC) is the "gold standard" for measuring energy expenditure (EE) and thus would intuitively anticipate that its use would be needed to provide optimal nutrition support in critical illness. Recent studies in the literature as well as dramatic changes in clinical practice over the past decade, though, would suggest that such a precise measure by IC to set energy goals is not required to maximize clinical benefit from early feeding in the intensive care unit (ICU). Results from randomized controlled trials evaluating permissive underfeeding, use of supplemental parenteral nutrition to achieve tight calorie control, and caloric density of formulas to increase energy delivery have provided an important perspective on 3 pertinent issues.
View Article and Find Full Text PDFEur Urol Oncol
April 2020
Urology Oncology, Fundacoió Puigvert, Barcelona, Spain.
Intravesical immunotherapy with bacille Calmette-Guérin (BCG) vaccine is the main treatment for non-muscle-invasive bladder cancer (NMIBC), with proven effects on reducing recurrence, progression, and death from NMIBC. However, it is not effective in all patients, and recurrence after adequate BCG therapy can frequently lead to progression to more life-threatening disease. This point-counterpoint review considers how to treat a healthy 60-yr-old patient with T1 high-grade NMIBC fitting the new definition of BCG-unresponsive disease, that is, persistent high-grade disease at 6-12mo, despite an adequate course of induction and maintenance with BCG.
View Article and Find Full Text PDFJ Dent Educ
March 2018
Dr. Chu is Associate Dean for Research and Professor of Biomedical and Applied Sciences, School of Dentistry, Indiana University; Dr. Makhoul is Assistant Professor, Faculty of Dentistry, McGill University; Dr. Silva is Chair, Section of Pediatric Dentistry, School of Dentistry, University of California, Los Angeles; Dr. Gonzales is Associate Dean for Curriculum and Strategic Communications Professor, College of Dental Medicine, Medical University of South Carolina; Dr. Letra is Associate Professor, Department of Diagnostic and Biomedical Sciences, University of Texas School of Dentistry at Houston; and Dr. Mays is Associate Dean of Academic Affairs, School of Dentistry, University of Minnesota.
This Point/Counterpoint article addresses a long-standing but still-unresolved debate on the advantages and disadvantages of using live patients in dental licensure exams. Two contrasting viewpoints are presented. Viewpoint 1 supports the traditional use of live patients, arguing that other assessment models have not yet been demonstrated to be viable alternatives to the actual treatment of patients in the clinical licensure process.
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