Meningiomas are tumours typically derived from the meningothelial cells of the arachnoid mater. They most often arise in intracranial, intraspinal, or orbital locations. Ectopic meningiomas, described as primary meningiomas with no intracranial involvement, are definitely unconventional. In fact, most of the extracranial meningiomas described in the literature, particularly in the outer ear, are effectively spreads of disease with primary intracranial localization. We describe a case of a primary external auditory canal meningioma with demonstrated absence of intracranial involvement, and we provide a full radiological, histological, immunohistochemical and molecular characterization of the lesion.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.prp.2023.154963 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Department of Neurobiology, Harvard Medical School, Boston, MA 02115.
The sense of hearing originates in the cochlea, which detects sounds across dynamic sensory environments. Like other peripheral organs, the cochlea is subjected to environmental insults, including loud, damage-inducing sounds. In response to internal and external stimuli, the central nervous system directly modulates cochlear function through olivocochlear neurons (OCNs), which are located in the brainstem and innervate the cochlear sensory epithelium.
View Article and Find Full Text PDFIran J Otorhinolaryngol
January 2025
Department of Otorhinolaryngology, Faculty of Medicine, Alexandria University, Egypt.
Introduction: Scleroma is a chronic, specific granulomatous disease that affects the head and neck mucosa. Its common sites are the nose and larynx; however, it might affect other areas. One of the rare sites to be affected is the middle ear and mastoid cavity, for which the term otoscleroma was coined.
View Article and Find Full Text PDFeNeuro
January 2025
Research School of Psychology, Australian National University, 0200, Australia.
Inner speech refers to the silent production of language in one's mind. As a purely mental action without obvious physical manifestations, inner speech has been notoriously difficult to quantify. Inner speech is thought to be closely related to overt speech.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Modelling of Cognitive Processes, Berlin Institute of Technology, Berlin 10587, Germany.
Neuronal processing of external sensory input is shaped by internally generated top-down information. In the neocortex, top-down projections primarily target layer 1, which contains NDNF (neuron-derived neurotrophic factor)-expressing interneurons and the dendrites of pyramidal cells. Here, we investigate the hypothesis that NDNF interneurons shape cortical computations in an unconventional, layer-specific way, by exerting presynaptic inhibition on synapses in layer 1 while leaving synapses in deeper layers unaffected.
View Article and Find Full Text PDFCureus
December 2024
Department of Otolaryngology, Head and Neck Surgery, Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, GBR.
Objectives To assess the dimensions of external ear (pinna) in different age groups in the North Indian population. To assess the mean dimensions of external ear (pinna) in different age groups in North Indian males and females. Methods The study area was Lucknow/Barabanki, Uttar Pradesh, and the study center was Era's Lucknow Medical College, Uttar Pradesh, India.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!