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http://dx.doi.org/10.3389/fmicb.2023.1304997 | DOI Listing |
Int J Gynaecol Obstet
January 2025
Guy's & St Thomas' Hospital Foundation Trust, London, UK.
The number of retractions of randomized clinical trials (RCTs) following post-publication allegations of misconduct is increasing. To address this issue, we aimed to establish an international multistakeholder consensus on post-publication integrity concerns related to RCTs. After prospective registration (https://osf.
View Article and Find Full Text PDFEarly Interv Psychiatry
February 2025
Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
We argue that while a substantial proportion of emerging adults are in post-secondary education, there is relatively little consideration of this context within research and policy around youth mental health. The unique challenges young adults face in post-secondary education overlay underlying risk factors experienced by emerging adults. While post-secondary education facilitates social mobility, it also introduces stressors such as academic demands, financial insecurity and social isolation.
View Article and Find Full Text PDFFront Plant Sci
January 2025
Cell Biology Group - Instituto para la Conservación y Mejora de la Agrodiversidad Valenciana (COMAV) Institute, Universitat Politècnica de València, Valencia, Spain.
Calcium (Ca) is a universal signaling cation with a prominent role as second messenger in many different plant processes, including sexual reproduction. However, there is much less knowledge about the involvement of Ca during embryogenesis processes. In this work we performed a study of Ca levels during the different stages of microspore embryogenesis in , with special attention to how Ca can influence the occurrence of different embryogenic structures with different embryogenic potential.
View Article and Find Full Text PDFFront Mol Biosci
January 2025
Faculty of Biology and Biotechnologies, National Research University Higher School of Economics, Moscow, Russia.
Introduction: Colorectal cancer (CRC) is characterized by an extremely high mortality rate, mainly caused by the high metastatic potential of this type of cancer. To date, chemotherapy remains the backbone of the treatment of metastatic colorectal cancer. Three main chemotherapeutic drugs used for the treatment of metastatic colorectal cancer are 5-fluorouracil, oxaliplatin and irinotecan which is metabolized to an active compound SN-38.
View Article and Find Full Text PDFBMJ Oncol
January 2024
Department of Radiology, University of Washington, Seattle, Washington, USA.
Oncology is becoming increasingly personalised through advancements in precision in diagnostics and therapeutics, with more and more data available on both ends to create individualised plans. The depth and breadth of data are outpacing our natural ability to interpret it. Artificial intelligence (AI) provides a solution to ingest and digest this data deluge to improve detection, prediction and skill development.
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