AI Article Synopsis
- Vitamin C-based cluster therapy (HAT), which includes hydrocortisone, vitamin C, and thiamine, is a new potential treatment for sepsis alongside conventional methods.
- While there is a strong theoretical basis for this therapy, its effectiveness in clinical settings is still unclear.
- The review evaluates existing studies on HAT therapy’s efficacy and aims to guide future clinical applications for treating sepsis.
Article Abstract
Vitamin C-based cluster therapy, which involves the combined application of hydrocortisone, vitamin C, and thiamine (HAT), is a recently proposed new treatment option for sepsis on top of conventional treatment. This therapy has a strong theoretical basis, but its clinical efficacy remains inconclusive. This review summarizes the rationale for HAT therapy for sepsis and describes the evaluation of its efficacy in clinical observational studies and randomized controlled trials, with the aim of providing a reference for the future clinical practice application of HAT therapy in sepsis.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658041 | PMC |
| http://dx.doi.org/10.1016/j.jointm.2023.04.003 | DOI Listing |
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