AI Article Synopsis
- Endometrial neuroendocrine carcinoma is a rare but aggressive type of endometrial cancer, categorized into carcinoid (low grade) and small- and large-cell (high grade) types, with few global reports on the carcinoid variety.
- A case of mixed endometrial carcinoma, combining carcinoid and squamous cell types, is presented, characterized by symptoms like vaginal bleeding and low sodium levels.
- Future research is needed to improve diagnosis and treatment strategies for this uncommon disease.
Article Abstract
Introduction: Histologically, endometrial neuroendocrine carcinoma is an extremely rare pathological type of endometrial cancer. In addition, this type is characterized by high invasiveness and poor clinical outcome, which was classified into carcinoid (low grade), and small-cell and large-cell neuroendocrine carcinoma (high grade). Globally, reports on endometrial carcinoid carcinoma are limited. Clinically, it is also rare to see primary squamous cell carcinoma of endometrium.
Case Presentation: Here, we report an interesting case of mixed carcinoma of endometrium with both carcinoid and squamous cell carcinoma, which presented with persistent vaginal bleeding and hyponatremia.
Conclusion: Careful pathologic review is necessary to diagnose this rare disease. More studies in the future are warranted to demonstrate the primary surgical treatments and the efficacy of adjuvant therapy of this disease.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651180 | PMC |
| http://dx.doi.org/10.1159/000534622 | DOI Listing |
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