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http://dx.doi.org/10.3389/fped.2023.1328201 | DOI Listing |
Ann Rheum Dis
January 2025
International Drug Development Institute, Louvain-la-Neuve, Belgium; I-BioStat, Hasselt University, Hasselt, Belgium.
Front Immunol
January 2025
Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, United States.
While durable antibody responses from long-lived plasma cell (LLPC) populations are important for protection against pathogens, LLPC may be harmful if they produce antibodies against self-proteins or self-nuclear antigens as occurs in autoimmune diseases such as systemic lupus erythematosus (SLE). Thus, the elimination of autoreactive LLPC may improve the treatment of antibody-driven autoimmune diseases. However, LLPC remain a challenging therapeutic target.
View Article and Find Full Text PDFEnviron Manage
January 2025
TECNALIA Research & Innovation, Basque Research and Technology Alliance (BRTA), Energy, climate, and urban transition, Parque Tecnológico de Bizkaia, Derio, Spain.
The extent and timescale of climate change impacts remain uncertain, including global temperature increase, sea level rise, and more frequent and intense extreme events. Uncertainties are compounded by cascading effects. Nevertheless, decision-makers must take action.
View Article and Find Full Text PDFFront Nutr
January 2025
Møreforsking, Volda, Norway.
Front Psychol
January 2025
Department of Psychological Medicine, Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Background: Many people with depression, for which self-blame plays a key role, are not amenable to current standard psychological treatments. This calls for novel self-guided interventions, which require less attention and motivation. The present study sought to establish proof-of-concept for a novel self-guided intervention in a non-clinical sample, which prompts people to transform self-blaming feelings into "longing," as a related unpleasant, but presumably more adaptive and approach-related emotion, which plays a key role in many musical and literary genres but has been largely overlooked in clinical research.
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