AI Article Synopsis
- The study investigates how corneal epithelial thickness changes after ICRS implantation in keratoconus patients using advanced imaging technology.
- A total of 40 mild to moderate keratoconus patients underwent surgery, and significant increases in epithelial thickness were observed at one, three, and six months post-operation.
- The findings suggest that ICRS implantation not only helps modify the corneal shape but also leads to a thicker and more regular epithelium as a reaction to the changes in the corneal structure.
Article Abstract
Purpose: To study the compensatory corneal epithelial changes after femtolaser-assisted intracorneal ring segment (ICRS) implantation in early and moderate cases of keratoconus (KC) using anterior segment optical coherence tomography (AS-OCT).
Patients And Methods: A prospective observational non-randomized study of 40 eyes with mild to moderate KC received femtolaser-assisted ICRS implantation. Ferrara ICRS with different arc lengths and thicknesses were used according to the patients' tomographic pattern. Patients had a clear central cornea, keratometry reading < 60 diopters, and corneal thickness > 400 microns. AS-OCT was performed preoperatively and at 1, 3, and 6 months after surgery. Corneal epithelial thickness (CET) was measured over 17 points (2 mm central and 16 points on 2-5 mm and 5-7 mm annular zones) over the pupil center. All data were collected and analyzed.
Results: Comparing the preoperative and postoperative data, there was a statistically significant increase in the CET postoperatively throughout the 6-month follow-up period in all zones (p<0.001). The epithelial thickness (ET) was noticed shortly around and central to the ring ridges by the first month (5-7 mm zone). By the third month, the flattened central cornea (2 mm zone) and the 2-5 mm zone showed a significant increase in ET up to the 6th month.
Conclusion: ICRS implantation in KC results in a thicker and more regular epithelium in the central corneal zone as a secondary response to the corneal stromal changes induced by the implants.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676668 | PMC |
| http://dx.doi.org/10.2147/OPTH.S432446 | DOI Listing |
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