Molecular phylogenetic and chemical analyses, and morphological characterization of collections of North American specimens support the description of two new species and two new combinations for known species. is a pathogen of (Orthoptera) from the Pacific Northwest USA and is a pathogen of cicadae (Hemiptera) from the Southeast USA. New combinations are made for and based on morphological, ecological, and chemical study. A new cyclopeptide family proved indispensable in providing chemotaxonomic markers for resolving species in degraded herbarium specimens for which DNA sequencing is intractable. This approach enabled the critical linkage of a 142-year-old type specimen to a phylogenetic clade. The diversity of in North America and the utility of chemotaxonomy for the genus are discussed.
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http://dx.doi.org/10.3897/mycokeys.100.110959 | DOI Listing |
Curr Med Chem
January 2025
Shree S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, 384012, India.
Aims: This study aimed to develop Imatinib Mesylate (IMT)-loaded Poly Lactic-co-Glycolic Acid (PLGA)-D-α-tocopheryl polyethylene glycol succinate (TPGS)- Polyethylene glycol (PEG) hybrid nanoparticles (CSLHNPs) with optimized physicochemical properties for targeted delivery to glioblastoma multiforme.
Background: Glioblastoma multiforme (GBM) is the most destructive type of brain tumor with several complications. Currently, most treatments for drug delivery for this disease face challenges due to the poor blood-brain barrier (BBB) and lack of site-specific delivery.
Curr Mol Med
January 2025
Department of Anesthesiology, Baoan Central Hospital of Shenzhen, Shenzhen, Guangdong Province, China.
Background: Morphine, a mu-opioid receptor (MOR) agonist commonly utilized in clinical settings alongside chemotherapy to manage chronic pain in cancer patients, has exhibited contradictory effects on cancer, displaying specificity toward certain cancer types and doses.
Objective: The aim of this study was to conduct a systematic assessment and comparison of the impacts of morphine on three distinct cancer models in a preclinical setting.
Methods: Viability and apoptosis assays were conducted on a panel of cancer cell lines following treatment with morphine, chemotherapy drugs alone, or their combination.
Front Parasitol
October 2024
Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.
Background: Schistosomiasis is caused by infection with parasitic worms and affects more than 250 million people globally. The detection of schistosome derived circulating cathodic and anodic antigens (CCA and CAA) has proven highly valuable for detecting active infections, causing both intestinal and urinary schistosomiasis.
Aim: The combined detection of CCA and CAA was explored to improve accuracy in detecting infections.
MycoKeys
January 2025
The Key Laboratory for Silviculture and Conservation of the Ministry of Education, Beijing Forestry University, Beijing 100083, China Beijing Forestry University Beijing China.
During the fungal investigations of hosts in China, ten isolates of were obtained from dead and dying branches. Morphological characteristics and phylogenetic analyses of combined ITS, LSU, and loci revealed the presence of two new species, and , as well as two new host records for and from . In this study, we provide descriptions and illustrations of these species, thereby enriching the diversity within the taxa.
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January 2025
College of Forestry, Guizhou University, CN-550025, Guiyang, Guizhou, China.
X.X.Bai & F.
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