AI Article Synopsis

  • The study investigates the link between P-wave duration (PWD) and the cardio-ankle vascular index (CAVI) in patients with obstructive sleep apnea (OSA), as both are indicators of potential heart issues.
  • Researchers analyzed data from 300 patients, finding a significant correlation between increased PWD and CAVI values, suggesting that greater arterial stiffness relates to delays in atrial conduction.
  • The results indicate that higher levels of arterial stiffness in OSA patients are associated with increased risks of atrial fibrillation due to impaired heart function.

Article Abstract

Aim: Prolonged P-wave duration (PWD), which indicates atrial conduction delay, is a potent precursor of atrial fibrillation (AF) that may be induced by obstructive sleep apnea (OSA). The cardio-ankle vascular index (CAVI), which is an arterial stiffness parameter, is elevated in patients with OSA; moreover, an increased CAVI is associated with atrial conduction delay through left atrium enlargement in association with left ventricular diastolic dysfunction. We aimed to examine the relationship between the CAVI and PWD in patients with OSA.

Methods: We included patients with a sinus rhythm who underwent overnight polysomnography. We measured the PWD and CAVI on standard 12-lead electrocardiograms; further, we analyzed the relationship between PWD and CAVI.

Results: We analyzed data from 300 participants (men, 89.0%; mean age, 52.3 ± 13.1 years; and body mass index, 26.2 ± 3.9 kg/m). The mean PWD was 104.4 ± 10.4 ms while the mean CAVI was 7.5 ± 1.5. PWD was significantly correlated with CAVI (r = 0.478, < 0.001); additionally, PWD and CAVI were directly associated with OSA severity ( = 0.002 and = 0.002, respectively). Multivariate regression analysis revealed an independent significant correlation of PWD and CAVI with OSA severity.

Conclusion: In patients with OSA, an increase in arterial stiffness is associated with atrial conduction delay.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10655741PMC
http://dx.doi.org/10.2147/VHRM.S428713DOI Listing

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