This review article provides a comprehensive overview of recent advancements in electron transport materials derived from quinoxaline, along with their applications in various electronic devices. We focus on their utilization in organic solar cells (OSCs), dye-sensitized solar cells (DSSCs), organic field-effect transistors (OFETs), organic-light emitting diodes (OLEDs) and other organic electronic technologies. Notably, the potential of quinoxaline derivatives as non-fullerene acceptors in OSCs, auxiliary acceptors and bridging materials in DSSCs, and n-type semiconductors in transistor devices is discussed in detail. Additionally, their significance as thermally activated delayed fluorescence emitters and chromophores for OLEDs, sensors and electrochromic devices is explored. The review emphasizes the remarkable characteristics and versatility of quinoxaline derivatives in electron transport applications. Furthermore, ongoing research efforts aimed at enhancing their performance and addressing key challenges in various applications are presented.
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http://dx.doi.org/10.3762/bjoc.19.124 | DOI Listing |
Molecules
February 2025
School of Electronic Science and Engineering, Xiamen University, Xiamen 361005, China.
Molecular design strategies such as noncovalent conformational locks, self-assembly, and D-A molecular skeletons have been extensively used to devise efficient and stable hole transport materials. Nevertheless, most of the existing excellent examples involve only single or dual strategies, and triple strategies remain scarcely reported. Herein, we attempt to develop two quinoxaline-based hole transport materials ( and ) through a triple strategy encompassing an S···N noncovalent conformational lock, D-A molecular skeletons, and self-assembly or conjugate engineering.
View Article and Find Full Text PDFOrg Lett
March 2025
Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.
The asymmetric -selective hydrogenation of arenes has long been a significant challenge. In this work, we were able to control the / selectivity in ruthenium-catalyzed asymmetric hydrogenation of 2,3-disubstituted quinoxalines by varying the catalyst counteranion. Using density functional theory calculations, we investigated the weak interactions─such as CH/π and hydrogen bonding─among the counteranion, the catalyst framework, and the substrate, elucidating the fundamental influence of counteranions on / selectivity in the asymmetric hydrogenation of quinoxalines.
View Article and Find Full Text PDFBioorg Med Chem Lett
March 2025
Department of Chemistry, Birla Institute of Technology and Science, Pilani, Hyderabad Campus, Jawahar Nagar, Kapra Mandal, Hyderabad 500078, Telangana, India. Electronic address:
In this work, novel 2-substituted-3-((1-substituted-1H-1,2,3-triazol-4-yl) methoxy) quinoxaline analogues were designed, synthesized, and various analytical techniques, viz., H NMR, C NMR, and Mass spectrometry, were deployed in the structure confirmation of the final compounds. Synthesized derivatives were evaluated for their antimycobacterial activity against Mycobacterium tuberculosis (Mtb) H37Rv.
View Article and Find Full Text PDFChemistry
March 2025
Visva-Bharati University: Visva-Bharati, Chemistry, Santiniketan Road, 731235, Santiniketan, Bolpur, INDIA.
Herein, we disclosed a copper-catalyzed carbogermylation of alkenes through 3,4-difunctionalization of quinoxalin-2(1H)-one to afford 3-oxo-3,4-dihydroquinoxaline 1-oxide incorporated organogermanium derivatives. Despite extensive research on the C-H functionalization of quinoxaline-2(1H)-one, the difunctionalization of this compound through C-C and N-O bond formation via the radical relay process is unusual. DFT calculation and mechanistic studies reveal that the reaction follows a radical pathway.
View Article and Find Full Text PDFEur J Med Chem
March 2025
Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, 500037, India. Electronic address:
Anti-microbial resistance has become a serious global health issue affecting millions of people worldwide. Despite extensive drug discovery efforts aimed at identifying potent molecules for effective anti-microbial treatments, the emergence of superbugs remains a significant challenge. Thus, developing novel therapeutic agents is required to combat these evolving threats.
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