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| http://dx.doi.org/10.1002/jha2.776 | DOI Listing |
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A Case Study of a Female Infant With Primary Hypertrophic Osteoarthropathy Demonstrates That Early Initiation of Celecoxib Slows but Does Not Prevent Symptom Progression.
Am J Med Genet A
January 2025
Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Primary Hypertrophic Osteoarthropathy (PHOAR1) is characterized by autosomal recessive loss of function variants in 15-hydroxyprostaglandin dehydrogenase (HPGD) leading to digital clubbing, periostosis, pachydermia, and severe hyperhidrosis. HPGD catalyzes the first step of prostaglandin E2 (PGE2) degradation. Selective COX-2 inhibitors have proved beneficial in adults, though it is unknown if early initiation of COX-2 inhibitors can alter the natural history of PHOAR1.
View Article and Find Full Text PDFSurgical management of single-level thoracolumbar vertebral body segmentation and formation failure causing progressive thoracolumbar myelopathy in three adult large-breed dogs.
Front Vet Sci
January 2025
Lumbry Park Veterinary Specialists, Hampshire, United Kingdom.
Objective: This study aimed to evaluate the medium-term outcome following spinal cord decompression and instrumented fixation of single-level congenital thoracolumbar vertebral malformations, characterized by combined failures of segmentation and formation, causing thoracolumbar myelopathy in three large-breed dogs.
Study Design: This was a retrospective clinical study.
Animals: The animals involved in the study were three large-breed dogs.
Documentation of ethnoveterinary knowledge and alternative practices for cattle tick control in Sekhukhune District, Limpopo Province, South Africa.
Front Vet Sci
January 2025
Department of Life and Consumer Sciences, Faculty of Agriculture and Life Sciences, University of South Africa, Pretoria, South Africa.
Introduction: The integration of traditional plant-based methods for controlling ectoparasites in the primary healthcare of livestock is progressively emerging as a crucial intervention to enhance livestock productivity in regions with limited resources, particularly in smallholder farming areas facing resource constraints. In Sekhukhune District, where livestock plays a vital role in rural livelihoods, cattle ticks present a significant challenge to cattle farming. This study aimed to document the ethnoveterinary practices employed by local communities to control cattle ticks, highlighting the use of alternative methods rooted in indigenous knowledge (IK).
View Article and Find Full Text PDFMonostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report.
Iran J Med Sci
December 2024
Department of Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Fibrous dysplasia is a slow-progressing benign condition characterized by abnormal bone formation that leads to some skeletal disorders. Although some of the fibrous dysplasia have unusual clinical and radiographic features that can lead to a challenging diagnosis, most lesions reveal an expansile bone defect due to cortex thinning. This report presented a case of monostotic fibrous dysplasia of a 43-year-old woman with involvement of the right maxillary jaw and sinuses, which indicated unusual histopathological features.
View Article and Find Full Text PDFExoskeleton Training for Spinal Cord Injury Neuropathic Pain (ExSCIP): Protocol for a Phase 2 Feasibility Randomised Trial.
HRB Open Res
September 2024
UCD School of Public Health, Physiotherapy and Sports Science, Health Sciences Centre, University College Dublin, Dublin, Leinster, Ireland.
Background: Following Spinal Cord Injury (SCI), 53% of people develop neuropathic pain (NP). NP can be more debilitating than other consequences of SCI, and a persistent health issue. Pharmacotherapies are commonly recommended for NP management in SCI, although severe pain often remains refractory to these treatments in many sufferers.
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