•India and Pakistan share a common public health concern: rabies, which affects both humans and animals.•Both countries have established national rabies control initiatives, but these programs face challenges such as inadequate funding and limited access to healthcare in rural areas.•Non-governmental organizations (NGOs) are also working to control rabies in both India and Pakistan.•Cross-Border Cooperation Crucial in Rabies Fight: SAARC Initiatives Promoting Regional Prevention.•Crucial Steps: Raising Rabies Awareness and Accessible PEP in Both Countries.
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http://dx.doi.org/10.1016/j.nmni.2023.101191 | DOI Listing |
J Epidemiol Glob Health
January 2025
Department of Community Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Background: Rabies is a preventable yet deadly public health threat. Despite the availability of effective vaccines for both humans and animals, the persistence of rabies-related fatalities underscores the need for enhanced public education strategies. This study aimed to develop and validate a Rabies Health Education Module delivered via a Massive Open Online Course, targeting adult dog owners in Kelantan, Malaysia.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China. Electronic address:
Rabies virus (RABV) is extremely hazardous to both humans and animals, causing up to 100 % death. Accurate and easy-to-use serological evaluation of vaccine potency following immunization is crucial for rabies control. In this study, recombinant RABV glycoprotein (rG) was designed and produced in 293FT cells.
View Article and Find Full Text PDFViruses
December 2024
School of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China.
Canids act as a crucial intermediary in the transmission of rabies and , serving as co-infection hosts and pathogen carriers for both rabies and hydatid disease (HD) transmitted from animals to humans. Therefore, an effective and efficient bivalent oral vaccine for preventing HD and rabies is urgently required to reduce economic losses in husbandry resulting from rabies and HD. In this study, a full-length plasmid (pcDNA4-NPM+G+EgM123+eGFP+L) carrying the gene and fluorescence reporter genes of eGFP and four auxiliary transfection plasmids of rabies virus SRV (pcDNA4-N, pcDNA4-P, pcDNA4-G, pcDNA-L) were established by reverse genetics approaches and co-transfected to BSR cells by electrotransfection.
View Article and Find Full Text PDFLancet Planet Health
January 2025
San Diego Zoo Wildlife Alliance, San Diego, CA, USA; VetinWild, Nanyuki, Kenya.
Despite increasing emphasis being placed on the inclusion of upstream ecological and social perspectives for zoonotic disease control, few guidelines exist for practitioners and decision makers to work with communities in identifying suitable, locally relevant interventions and integrating these into public health action plans. With an interdisciplinary group of Kenyan stakeholders, we designed and tested a comprehensive framework for the co-design, evaluation, and prioritisation of beneficiary-oriented, ecologically and socially informed interventions for preventing and controlling outbreaks of wildlife-borne zoonoses. Our approach used four globally important wildlife-borne pathogens-Rift Valley fever virus, Congo-Crimean haemorrhagic fever virus, and the causative agents of anthrax and rabies-enabling stakeholders to develop a shared understanding of complex transmission pathways, identify a broad array of measures targeting ecological, biological, and social processes governing outbreaks of these pathogens, and explore trade-offs for specific interventions.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Veterinary Epidemiology and Public Health, College of Veterinary Medicine and Animal Sciences, University of Gondar, P. O. Box 196, Gondar, Ethiopia.
Unlabelled: Knowledge of domestic dog ecology and demography has been recognized as central to the design of an effective rabies control program. The study was conducted to assess owned dogs' ecology and demography and to identify predictors associated with dog ownership and rabies occurrence in the Amhara region, Ethiopia.
Method: ology: The study employed dog census and questionnaire surveys of 907 households selected using a multistage sampling technique from six rural and six urban districts of the Amhara region, Ethiopia.
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