An overview of recent treatment options for primary sclerosing cholangitis.

Ann Gastroenterol

Department of Gastroenterology, University Hospital of Ioannina, Greece (Ioanna Mousavere, Fotios Fousekis, Gerasimos Baltayiannis, Dimitrios Christodoulou).

Published: October 2023

Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities targeting the inflammatory aspects have been suggested, but a consensus on the best treatment option is lacking. This study aims to review the most up-to-date treatment options for PSC.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662072PMC
http://dx.doi.org/10.20524/aog.2023.0834DOI Listing

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