Is Lung Function Measured by Oscillometry Useful in Interstitial Lung Diseases?

Introduction: The role of oscillometry in interstitial lung disease (ILD) is still unclear. The main objective of our study was to describe the parameters determined by oscillometry in these patients and compare them with those obtained in conventional respiratory function tests.

Methods: This was a cross-sectional observational study. Patients with no respiratory disease and patients being followed up for ILD in the specialist unit of Hospital Universitario de Getafe, Madrid were included.

Results: A total of 45 individuals were analyzed. Fifteen had no respiratory disease, 15 were ILD patients with mild functional impairment, and another 15 were ILD patients with severe impairment. None of the participants had an obstructive pattern on spirometry.Comparison between the three groups showed statistically significant differences in the values of R5-19, reactance at 5 Hz and reactance at 11 Hz. No differences were observed between the three groups in Delta Xrs. The study showed a strong correlation between total and inspiratory reactance at 5 Hz and forced vital capacity and diffusing capacity for carbon monoxide.

Conclusions: Our results suggest that the findings in ILD are characteristic of this disease and that they differ from those found in other diseases such as chronic obstructive pulmonary disease. It also seems that there are differences according to the degree of functional impairment of the patients. The results show a strong correlation with standard pulmonary function tests, so oscillometry could be a useful tool in patients with ILD who are unable to perform it, and could provide additional information.