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| http://dx.doi.org/10.18683/germs.2022.1348 | DOI Listing |
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Antimicrobial and anti-biofilm activity of a mucoadhesive hydrogel functionalized with aminochalcone on titanium surfaces and in Galleria mellonella model: In vitro and in vivo study.
Microb Pathog
January 2025
Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil. Electronic address:
Peri-implantitis associated with dental implants shares characteristics with destructive periodontal diseases. Both conditions are multifactorial and strongly correlated with the presence of microorganisms surrounding the prostheses or natural dentition. This study aimed to evaluate the antimicrobial activity and toxicity of a mucoadhesive hydrogel functionalized with aminochalcone (HAM-15) against Aggregatibacter actinomycetemcomitans, Fusobacterium periodonticum, Prevotella intermedia, Porphyromonas gingivalis, Tannerella forsythia, and Candida albicans.
View Article and Find Full Text PDFMicrobial boundaries in peri-implantitis: a review of pathogen-related advances.
Folia Med (Plovdiv)
December 2024
University of Baghdad, Baghdad, Iraq.
In the field of implantology, peri-implantitis is still a common complication of implant failure. Similar to periodontal disease, this kind of pathological condition is characterized by inflammation of the tissues surrounding dental implants or fillings. The sources of infection have been shown to be chronic periodontitis and poor maintenance of the communion.
View Article and Find Full Text PDFEffect of atorvastatin gel in non-surgical treatment of peri-implant mucositis: A randomized controlled clinical trial.
J Adv Periodontol Implant Dent
September 2024
Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Background: Peri-implant diseases, such as peri-implant mucositis and peri-implantitis, are inflammatory conditions caused by biofilms that can lead to the loss of surrounding soft tissues and bone. The most effective treatment involves non-surgical mechanical debridement to remove plaque, but other treatment modalities have shown limited success. This study investigated the anti-inflammatory and immunomodulatory effects of atorvastatin (ATV) gel as an additional treatment for peri-implant mucositis.
View Article and Find Full Text PDFThe Role of Implant Coronal Surface Properties on Early Adhesion of Streptococcus Oralis-An In Vitro Comparative Study.
J Biomed Mater Res A
January 2025
Research and Development, ZimVie Dental, Palm Beach Gardens, Florida, USA.
Dental implant coronal surfaces designed with the primary goal of maintaining crestal bone levels may also promote bacterial adhesion, leading to soft tissue inflammation and peri-implant bone loss. Achieving an optimal surface roughness that minimizes bacterial adhesion while preserving crestal bone is crucial. It is hypothesized that a specific threshold surface roughness value may exist below which, and above which, initial bacterial adhesion does not statistically change.
View Article and Find Full Text PDFPotential Impact of Microbial Variations After Peri-Implantitis Treatment on Peri-Implant Clinical, Radiographic, and Crevicular Parameters: A Systematic Review.
Dent J (Basel)
December 2024
Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Salerno, Italy.
This systematic review evaluated concomitant trends in microbial (total biofilm load and pre-dominant pathogens' counts) and clinical, radiographic, and crevicular variations following (any) peri-implantitis treatment in partially vs. totally edentulous, systemically healthy, non-smoking adults and compared them to peri-implant mucositis treated sites. The study protocol, compliant with the PRISMA statement, was registered on PROSPERO (CRD42024514521).
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