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Electrospun nanofibers: Focus on local therapeutic delivery targeting infectious disease.
J Drug Deliv Sci Technol
February 2025
Department of Bioengineering, University of Louisville Speed School of Engineering, Louisville, KY, 40202.
Whether it be due to genetic variances, lack of patient adherence, or sub-optimal drug metabolism, the risk of antibiotic resistance from medications administered systemically continues to pose significant challenges to fighting infectious diseases. Ideally, infections would be treated locally for maximal efficacy while minimizing off-target effects. The electrospinning of biomaterials has recently facilitated the creation of electrospun nanofibers as an alternative delivery vehicle for local treatment.
View Article and Find Full Text PDFUnraveling 3d Transition Metal (Ni, Co, Mn, Fe, Cr, V) Ions Migration in Layered Oxide Cathodes: A Pathway to Superior Li-Ion and Na-Ion Battery Cathodes.
Adv Mater
January 2025
Institute of Science and Technology for New Energy, Xi'an Technological University, Xi'an, P. R. China.
Li-ion and Na-ion batteries are promising systems for powering electric vehicles and grid storage. Layered 3d transition metal oxides ATMO (A = Li, Na; TM = 3d transition metals; 0 < x ≤ 2) have drawn extensive attention as cathode materials due to their exceptional energy densities. However, they suffer from several technical challenges caused by crystal structure degradation associated with TM ions migration, such as poor cycling stability, inferior rate capability, significant voltage hysteresis, and serious voltage decay.
View Article and Find Full Text PDF[Application of Nano-drug Delivery Technology in Overcoming Drug Resistance in Lung Cancer].
Zhongguo Fei Ai Za Zhi
November 2024
Department of Medical Oncology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu 610042, China.
Lung cancer is one of the most malignant tumor, representing a significant threat to human health. In China, its mortality rate is the highest among all malignant tumors. The occurrence of drug resistance has resulted in unfavourable prognosis for patients with lung cancer, and overcoming drug resistance is a significant challenge that needs to be addressed.
View Article and Find Full Text PDFUsing fingermark powders and lifters on pangolin scales for anti-poaching measures.
Forensic Sci Int
January 2025
King's Forensics, Department of Analytical, Environmental and Forensic Sciences, King's College London, 150 Stamford Street, London SE1 9NH, UK. Electronic address:
Wildlife forensics is a relatively underexplored field of science. It provides forensic evidence to support legal investigations involving wildlife crime, such as the trafficking and poaching of animals and/or their goods. The consequences of poaching are not just limited to a decline in animal welfare and include the spread of zoonotic disease, species, cultural and habitat loss, and injury of anti-poaching rangers.
View Article and Find Full Text PDFExploring policy coherence for land use transformations: The case of Scotland.
J Environ Manage
January 2025
Scotland's Rural College (SRUC), Peter Wilson Building, Kings Buildings, Edinburgh, EH9 3JG, UK. Electronic address:
The multiple crises (climate, biodiversity, austerity) facing our socio-ecological systems require ambitious responses; with much of the responsibility for protecting public goods and developing sustainably lying with public policy. To tackle these wicked problems, there are increasing calls for policy coherence: to use the levers of government in a more holistic and systemic manner. Land use transformation is crucial to achieving these ambitions.
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