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Impact of diabetes mellitus on coronary artery plaque characteristics and outcomes in the SCOT-HEART trial.
J Cardiovasc Comput Tomogr
January 2025
British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, United Kingdom; Edinburgh Imaging, University of Edinburgh, United Kingdom. Electronic address:
Background: Diabetes mellitus is an established cardiovascular risk factor. We assessed the impact of diabetes mellitus on quantitative plaque and long-term outcomes in patients with and without diabetes mellitus in the Scottish COmputed Tomography of the HEART (SCOT-HEART) trial.
Methods: Coronary artery calcium (CAC) was assessed on non-contrast computed tomography (CT).
Aim: To evaluate characteristics of atherosclerotic plaques (ASP) remaining after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) by coronary computed tomography angiography (CCTA).
Material And Methods: Among 249 patients (193 men) with ACS aged 58±10 years, 183 (73.5%) had myocardial infarction, 66 (26.
Epicardial Adipose Tissue from Computed Tomography: a Missing Link in Premature Coronary Artery Disease?
Eur Heart J Cardiovasc Imaging
January 2025
Sorbonne Université, unité d'imagerie cardiovasculaire et thoracique, Hôpital La Pitié Salpêtrière (AP-HP), Laboratoire d'Imagerie Biomédicale, INSERM, CNRS, Institute of Cardiometabolism and Nutrition, ACTION Group, Paris, France.
Purpose: Epicardial adipose tissue (EAT) could contribute to the specific atherosclerosis profile observed in premature coronary artery disease (pCAD) characterized by accelerated plaque burden (calcified and non-calcified), high risk plaque features (HRP) and ischemic recurrence. Our aims were to describe EAT volume and density in pCAD compared to asymptomatic individuals matched on CV risk factors and to study their relationship with coronary plaque severity extension and vulnerability.
Materials And Methods: 208 patients who underwent coronary computed tomography angiography (CCTA) were analyzed.
Iron levels and vulnerable coronary atherosclerotic plaques.
Kardiol Pol
January 2025
Department of Coronary and Structural Heart Diseases, National Institute of Cardiology, Warszawa, Poland.
Background: Preliminary research indicates that higher iron levels are associated with worse outcomes in patients with coronary artery disease.
Aims: The study aimed to investigate the relationship between iron levels and the type and composition of coronary plaques.
Methods: In patients with ≥1 coronary stenosis ≥50% on computed tomography angiography, iron levels, presence of high-risk plaque features, such as low-attenuation plaque (LAP), napkin-ring sign, positive remodeling, and spotty calcium, as well as type and plaque composition (calcified/fibrous/fibro-fatty/necrotic core) were evaluated.
Psoriasis treatments in the stabilization of atherosclerosis: a systematic review.
Arch Dermatol Res
December 2024
Department of Biomedical Sciences, Tulane School of Medicine, New Orleans, LA, USA.
This systematic review explores the relationship between achieving minimal disease activity in psoriasis and the progression of atherosclerosis. It investigates how biologic therapies and other treatments impact atherosclerosis markers, offering insights into therapeutic strategies. A comprehensive search of PubMed, Embase, and Web of Science was conducted from January 1, 2000, to April 1, 2023, using terms such as psoriasis, psoriatic arthritis, atherosclerosis, biologic therapy, vascular stiffness, carotid intima-media thickness (CIMT), and coronary computed tomography angiography (CCTA).
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