AI Article Synopsis
- Organotypic slice cultures are better than regular cell cultures because they keep the 3-D shape and different types of cells from the tissue.
- These cultures can be tested with different substances to see how they might affect the tissue in real life.
- The text explains how to create organotypic slice cultures specifically from rat placenta.
Article Abstract
Organotypic slice cultures provide several advantages over primary and cell line culture models. Unlike monolayer cultures, organotypic slice cultures retain the tissue's 3-D architecture, multi-lineage cell populations, and many complex functional characteristics. Organotypic slice cultures can be exposed to biological, pharmacological, or environmental agents and analyzed to predict in vivo responses. Herein, we describe a method for preparing organotypic slice cultures generated from rat placenta.
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| http://dx.doi.org/10.1007/978-1-0716-3495-0_4 | DOI Listing |
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