Introduction: Parkinson's disease (PD) is a widespread neurodegenerative disorder characterised by wide range of symptoms. Freezing of gait (FoG), a transient feeling that the patient's feet are nailed to the floor, resulting in an inability to move, is a particularly distressful symptom. The assessment of FoG can be challenging. Often, clinicians are reliant on patients' subjective experiences and patient questionnaires such as the Freezing of Gait Questionnaire (FOGQ) and its updated version, the New FOGQ (NFOGQ).Until now, the NFOGQ has not been validated and piloted for use in Danish. Therefore, few attempts have been made to assess the prevalence and severity of FoG in Danish patients with PD.
Methods: This report describes a two-step process of adapting the NFOGQ into Danish and piloting its use among a cohort of patients with PD. A satisfactory translation (Danish NFOGQ) was produced and successfully piloted.
Results: The translation showed robust test-retest reliability after two weeks. Patients fully understood the questionnaire. Using the Danish NFOGQ in an online prevalence survey, we found that 35.7% of respondents had experienced FoG and that the prevalence correlated with disease duration.
Conclusion: The Danish NFOGQ appears to be appropriate for assessing FoG in Danish patients with PD in both clinical and research settings.
Funding: None.
Trial Registration: Not relevant.
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Front Neurol
January 2025
Department of Rehabilitation Sciences, Neurorehabilitation Research Group (eNRGy), KU Leuven, Leuven, Belgium.
Introduction: Freezing of gait (FOG) is a disabling symptom for people with Parkinson's disease (PwPD). Turning on the spot for one minute in alternating directions (360 turn) while performing a cognitive dual-task (DT) is a fast and sensitive way to provoke FOG. The FOG-index is a widely used wearable sensor-based algorithm to quantify FOG severity during turning.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Emergency and Outpatient Department, China-Japan Union Hospital of Jilin University, Changchun, China.
Background: Preliminary scientific evidence suggests that freezing of gait (FoG) in patients with Parkinson disease (PD) is linked to noradrenergic dysfunction in the locus coeruleus (LC). However, definitive findings regarding the correlation between FoG occurrence and the LC are lacking. This study thus aimed to investigate the relationship between the FoG occurrence and LC degeneration in patients with PD by analyzing the signal characteristics of the LC in neuromelanin-sensitive magnetic resonance imaging (NM-MRI).
View Article and Find Full Text PDFEur J Neurol
January 2025
Research Unit, Hospital Universitario Burgos, Burgos, Spain.
Background And Purpose: Adopting telemedicine (TM) enables improved access to specialized care and reduces barriers. The aim was to assess the cost-utility of a coadjutant multidisciplinary TM programme for fall prevention compared to standard in-office visits for individuals with Parkinson's disease (PD).
Methods: This was an 8-month single-blind randomized controlled trial.
Parkinsonism Relat Disord
January 2025
Chulalongkorn Centre of Excellence for Parkinson's Disease & Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, 10330, Thailand; The Academy of Science, The Royal Society of Thailand, Bangkok, 10330, Thailand. Electronic address:
Introduction: Detecting Freezing of Gait (FOG) poses challenges, with the subjective 6-item FOG Questionnaire relying solely on patient perception. We aim to create a holistic FOG Detection Toolkit combining subjective and objective elements (descriptions, images, and videos) to improve FOG detection precision.
Methods: Development of the FOG Detection Toolkit involved a detailed cover sheet on FOG and its triggers, along with video exemplars and a 4-item FOG-specific self-assessment questionnaire, all rigorously validated.
Sensors (Basel)
December 2024
Department of Neurology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Freezing of gait (FOG) is a debilitating symptom of Parkinson disease (PD). It is episodic and variable in nature, making assessment difficult. Wearable sensors used in conjunction with specialized algorithms, such as our group's pFOG algorithm, provide objective data to better understand this phenomenon.
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