Cascade alkyl migration of 2-alkynylanilines an aromaticity destruction and reconstruction process is reported. The first alkyl migration is triggered by generation of a dearomatized arenium species oxidation and cyclization, and the second is driven by the force to restore the aromaticity of rearrangement products. The reaction gave rise to a range of multi-functionalized indoles.
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| http://dx.doi.org/10.1039/d3cc04815b | DOI Listing |
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