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| http://dx.doi.org/10.14814/phy2.15874 | DOI Listing |
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Optical Imaging of Trigeminal Ganglion Excitation Evoked by Electrical Stimulation of the Trigeminal Nerve.
Cureus
December 2024
Division of Dental Anesthesiology, Faculty of Dentistry Graduate School of Medicine and Dental Sciences, Niigata University, Niigata, JPN.
Background There are many reports of anatomical and physiological studies on trigeminal ganglion neurons, but few studies have analyzed temporal changes in the excitation of the trigeminal ganglion. This study aimed to establish an experimental system for spatial and temporal imaging analysis of the excitatory dynamics of trigeminal ganglion cells evoked by stimulation of a peripheral branch of the trigeminal nerve. Methods After excision of the trigeminal ganglion with the inferior alveolar nerve (IAN) from Sprague Dawley rats (seven to nine weeks old), 400-µm-thick slices of the trigeminal ganglion with the IAN were prepared.
View Article and Find Full Text PDFSex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment.
Sleep Epidemiol
December 2024
Health through Physical Activity, Lifestyle and Sport Research Centre and Division of Physiological Sciences, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Background: Risk factors for cardiovascular disease (CVD) and sleep health are well-known to be sex- and race-specific. To build on the established relationship between sleep duration and CVD risk, this cross-sectional study aimed to describe sex-specific associations between CVD risk and other sleep characteristics (sleep quality, sleep timing and sleep onset latency) in low-income adults of African descent.
Methods: Self-reported sleep (Pittsburgh Sleep Quality Index [PSQI], Epworth Sleepiness Scale [ESS], Insomnia Severity Index [ISI]), demographic and lifestyle data were collected in 412 adults (56 % women, 35.
Permeable and Durable Liquid-Metal Fiber Mat as Implantable Physiological Electrodes with Long-Term Biocompatibility.
Adv Mater
January 2025
Department of Chemistry, Tsinghua University, Beijing, 100084, P. R. China.
Implantable physiological electrodes provide unprecedented opportunities for real-time and uninterrupted monitoring of biological signals. Most implantable electronics adopt thin-film substrates with low permeability that severely hampers tissue metabolism, impeding their long-term biocompatibility. Recent innovations have seen the advent of permeable electronics through the strategic modification of liquid metals (LMs) onto porous substrates.
View Article and Find Full Text PDFAre glucagon-like peptide-1 receptor agonists anti-consummatory drugs?
CNS Spectr
January 2025
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Incretin-based treatments, such as glucagon-like peptide-1 receptor (GLP-1R) agonists (eg liraglutide and semaglutide), have rapidly transformed obesity treatment. The well-documented weight loss effect from these agents is considered to be primarily a result of their actions on food intake, but frequent anecdotal reports from varied sources have suggested that they might also broadly affect consummatory behavior, including alcohol and drugs of abuse, suggesting a potential modulatory effect on reward behavior. Herein, we critically review the extant literature on the behavioral effects of GLP-1R agonists in humans, including their impact on feeding behavior, alcohol/drug intake, and overall reward response.
View Article and Find Full Text PDFDoes mental exertion during incremental exercise change substrate oxidation and cardiorespiratory outcomes in individuals with overweight?
Physiol Rep
January 2025
Department of Biological Sciences in Sport, Faculty of Sport Sciences and Health, Shahid Beheshti University, Tehran, Iran.
Given the growing concern over the impact of brain health in individuals with overweight, understanding how mental exertion (ME) during exercise affects substrate oxidation and cardiorespiratory outcomes is crucial. This study examines how ME impacts these outcomes during an incremental exercise test in adults with overweight. Seventeen adults who were overweight completed an incremental exercise test on a cycle ergometer two times, with and without the Stroop task.
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