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http://dx.doi.org/10.1097/JS9.0000000000000932DOI Listing

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Bowel Resection Outcomes in Ovarian Cancer Cytoreductive Surgery by Surgeon Specialty.

JAMA Surg

October 2024

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Tufts University School of Medicine, Boston, Massachusetts.

Importance: Extensive bowel surgery is often necessary to achieve complete cytoreduction in patients with epithelial ovarian cancer. Regardless of who performs the surgery, it has been well documented that bowel resections are a high-risk procedure and an anastomotic leak is a severe complication that can occur. There are few studies addressing whether surgeon type impacts surgical outcomes in this patient population.

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Article Synopsis
  • * Research is looking into plasma-activated liquids (PAL) as a potential adjuvant treatment to reduce side effects and protect healthy tissue during peritoneal cancer therapy.
  • * Studies showed that human peritoneal macrophages exposed to PAL displayed resistance by increasing proliferation and anti-oxidative pathways, suggesting PAL might have beneficial immunomodulatory effects for treating peritoneal cancer.
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