Comparing neuropsychological functioning in Turkish patients with right and left temporal lobe epilepsy.

Appl Neuropsychol Adult

Department of Psychiatry, Istanbul Medeniyet University, Goztepe Training, and Research Hospital, Istanbul,Turkey.

Published: November 2023

AI Article Synopsis

  • A study compared neuropsychiatric evaluations between left-sided (LTLE) and right-sided (RTLE) temporal lobe epilepsy patients, with LTLE making up 68.3% of participants.
  • Results showed significant differences in performance on various cognitive tests, with LTLE patients generally scoring lower in memory and verbal fluency tasks compared to RTLE patients.
  • The findings suggest that specific cognitive tests, like those from the Wechsler scales, can help determine which hemisphere is affected in temporal lobe epilepsy cases.

Article Abstract

We compared neuropsychiatric evaluations in temporal lobe epilepsy according to the lateralized hemisphere. Forty-one (68.3%) left-sided temporal lobe epilepsy (LTLE) were compared to 19 right-sided temporal lobe epilepsy (RTLE) (31.7%) ( < 0.001). RTLE mean age was 37 (22-46) years, and LTLE mean age 38 was (30-42). RTLE disease duration was 10 (6-20) years, and LTLE was 22 (10-33) ( < 0.013). Gender (man/woman) for RTLE was 7/12, and for LTLE was 18/23. LTLE scored poorer on the Wechsler Memory Scale (WMS)-III's Mental Control Months-error, WMS-V's "Forward Number Range" and "Backward Number Range" than RTLE ( < 0.017,  < 0.023,  < 0.004). There were differences between hemispheres for "Number of Items Remembered with a Hint" and "Total number of Recalled Items" (WMS-IV) ( < 0.038,  < 0.045). LTLE had lower scores in the Verbal Fluency -K-A-S letters words and WAIS (Wechsler Adult Intelligence Scale) similarity than RTLE ( < 0.019,  < 0.024,  < 0.033,  < 0.026). Oktem and Boston-number of Self-Named Items Tests were poorer in LTLE than RTLE ( < 0.05,  < 0.043). Mental Control Months-error (WMS-III), "Total Number of Recalled Items", "Number of Items Remembered with Hint" (WMS-IV), forward and backward number range (WMS-V), Oktem, Verbal Fluency -K,-A,-S letters words, WAIS similarity, and Boston-number of Self-Named Items tests, can help identify lateralization, particularly in LTLE.

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Source
http://dx.doi.org/10.1080/23279095.2023.2286504DOI Listing

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