Shifting Strategies in the Treatment of Pediatric Craniopharyngioma.

Curr Oncol Rep

Department of Pediatric Neurosurgery and Pediatric Brain Institute, Dana Dwek Children Hospital, Tel Aviv Medical Center, 6 Weizmann Street, 64239, Tel Aviv, Israel.

Published: December 2023

Purpose Of Review: Craniopharyngiomas represent one of the most challenging diseases to treat. Despite their benign histology, and after many decades of surgical experience and technological advancements, there is still no clear consensus regarding the most effective management for this tumor. Due to their location and aggressive local characteristics, purely surgical approaches all too often result in unacceptable morbidity.

Recent Findings: Partial resection combined with radiation therapy results in similar control rates when compared to aggressive surgery, while also minimalizing the neuro-endocrinological morbidity. In this manuscript, we describe the historical progression of the shifting strategies in the management of pediatric craniopharyngioma. Time has also altered our expectations for outcomes, evolving from purely morbidity and mortality to simple Glasgow Outcomes Scales, now to formal neuro-psychometric and quality of life data.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11912-023-01471-9DOI Listing

Publication Analysis

Top Keywords

shifting strategies
8
pediatric craniopharyngioma
8
strategies treatment
4
treatment pediatric
4
craniopharyngioma purpose
4
purpose review
4
review craniopharyngiomas
4
craniopharyngiomas represent
4
represent challenging
4
challenging diseases
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!