We report the synthesis and characterization of two new fluorophores, consisting of a [8]cyclo--phenylene core in which two phenylenes are bridged by either a nitrogen atom or a carbonyl group. The nitrogen bridge increases the HOMO-LUMO gap, whereas the carbonyl bridge decreases it. These results provide guidelines to control the electronic properties of nanohoops.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d3cc04924h | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dorsal Root Ganglion Stimulation for Chronic Pelvic Pain Secondary to Endometriosis.
Neuromodulation
December 2024
Functional and Pain Clinic, Sao Paulo, SP, Brazil; Pediatric Neurosurgery, Washington University in St. Louis, St Louis, MO, USA. Electronic address:
Introduction: Chronic pelvic pain (CPP) is a multifaceted condition that poses significant challenges in clinical management owing to its complex and varied pathophysiology, including neuropathic, somatic, visceral, and musculoskeletal components. Endometriosis is frequently associated with CPP, necessitating a comprehensive, multimodal treatment strategy. This approach typically includes physical and behavioral therapy, pharmacologic interventions, surgical management of endometriosis, and various pain-modulating procedures.
View Article and Find Full Text PDFEnhancing intestinal absorption of a macromolecule through engineered probiotic yeast in the murine gastrointestinal tract.
Trends Biotechnol
December 2024
Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark. Electronic address:
Oral administration of therapeutic peptides is limited by poor intestinal absorption. Use of engineered microorganisms as drug delivery vehicles can overcome the challenges faced by conventional delivery methods. The potential of engineered microorganisms to act synergistically with the therapeutics they deliver opens new horizons for noninvasive treatment modalities.
View Article and Find Full Text PDFThe modulation of cholecystokinin receptor 1 in the NAc core input from VTA on METH-induced CPP acquisition.
Life Sci
December 2024
College of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification, Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology, Chinese Academy of Medical Sciences, Shijiazhuang, Hebei Province, China; Key Laboratory of Neural and Vascular Biology, Ministry of Education, Shijiazhuang, Hebei Province, China; Hainan Tropical Forensic Medicine Academician Workstation, Haikou, Hainan Province, China. Electronic address:
Article Synopsis
- - The study investigates how cholecystokinin (CCK) receptors, specifically CCK1 receptors, play a role in methamphetamine (METH)-induced addiction by affecting the nucleus accumbens core (NAcC) and its connections with other brain areas.
- - Using a mouse model, researchers created a condition that mimics METH addiction and explored the effects of genetically knocking out CCK receptor subtypes to understand their specific roles in the METH addiction process.
- - Results showed that disruption of CCK1R in NAcC hindered the development of METH-induced conditioned place preference and altered neuronal excitability, indicating that CCK1R is essential for the synaptic changes in the
The additive effect of 17β-estradiol on the modulation of electrochemotherapy with calcium ions or cisplatin in human clear carcinoma cells.
Biomed Pharmacother
December 2024
Department of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Wroclaw 50-556, Poland.
Calcium electroporation (CaEP) is an efficient approach for ovarian cancer treatment. It causes cell death by introducing elevated levels of calcium into cells. In this work, the research focused on two types of cell lines: CHO-K1, representing normal ovary cells, and OvBH-1, representing ovarian clear carcinoma cells.
View Article and Find Full Text PDFSerotonin acts through multiple cellular targets during an olfactory critical period.
iScience
November 2024
Departments of Biology and Neuroscience, West Virginia University, Morgantown, WV 26505, USA.
Serotonin (5-HT) modulates early development during critical periods when experience drives heightened levels of plasticity in neurons. Here, we investigate the cellular mechanisms by which 5-HT modulates critical period plasticity (CPP) in the olfactory system of . We first demonstrate that 5-HT is necessary for experience-dependent structural plasticity in response to chronic CO exposure and can re-open the critical period long after it normally closes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!