Comparison of Serum Per- and Polyfluoroalkyl Substances Concentrations in Incumbent and Recruit Firefighters and Longitudinal Assessment in Recruits.

Amy J Nematollahi Julia M Fisher Melissa A Furlong Paloma I Beamer Jaclyn M Goodrich Judith M Graber Antonia M Calafat Julianne Cook Botelho Shawn C Beitel Sally R Littau John J Gulotta Darin D Wallentine Jefferey L Burgess

J Occup Environ Med

From the Environmental Health Sciences, Mel and Enid Zuckerman School of Public Health, The University of Arizona, Tucson, Arizona (A.J.N., M.A.F., P.I.B., S.C.B., S.R.L., J.L.B.); BIO5 Institute, Statistics Consulting Laboratory, The University of Arizona, Tucson, Arizona (J.M.F.); University of Michigan School of Public Health, Ann Arbor, Michigan (J.M.Go.); School of Public Health, Rutgers, The State University of New Jersey, Piscataway, New Jersey (J.M.Gr.); Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia (A.M.C.); Tucson Fire Department, Tucson, Arizona (J.J.G.); and Sarasota County Fire Department, Sarasota, Florida (D.D.W.).

Published: March 2024

Firefighters are exposed to PFAS, and this study compared PFAS serum levels in current and new recruits to track changes over time.
99 incumbent firefighters and 55 recruits were tested for PFAS levels in 2015-2016, with follow-ups for recruits after 20-37 months, using various analytical methods.
Results showed that incumbents had lower PFAS levels than recruits, and most PFAS levels decreased in male recruits over time, with no connection found between firefighting exposure and PFAS levels.

Objective: Firefighters are occupationally exposed to per- and polyfluoroalkyl substances (PFAS). This study objective was to compare serum PFAS concentrations in incumbent and recruit firefighters and evaluate temporal trends among recruits.

Methods: Serum PFAS concentrations were measured in 99 incumbent and 55 recruit firefighters at enrollment in 2015-2016, with follow-up 20 to 37 months later for recruits. Linear and logistic regression and linear mixed-effects models were used for analyses. Fireground exposure impact on PFAS concentrations was investigated using adjusted linear and logistic regression models.

Results: Incumbents had lower n-PFOA and PFNA than recruits and most PFAS significantly decreased over time among male recruits. No significant links were found between cumulative fireground exposures and PFAS concentrations.

Conclusions: Serum PFAS concentrations were not increased in incumbent firefighters compared with recruits and were not associated with cumulative fireground exposures.

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10916718	PMC
http://dx.doi.org/10.1097/JOM.0000000000003020	DOI Listing

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