Meeting report: transposable elements at the crossroads of evolution, health and disease 2023.

Mob DNA

Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.

Published: November 2023

AI Article Synopsis

  • The conference on "Transposable Elements at the Crossroads of Evolution, Health and Disease" took place in Whistler, Canada, from September 3-6, 2023, organized by experts Kathleen Burns, Harmit Malik, and Irina Arkhipova.
  • It focused on the diverse interactions of transposable elements (TEs) with host organisms, exploring their potential to disrupt genes and promote evolutionary changes through novel gene products and functions.
  • The event featured six plenary sessions, two workshops, 50 talks, and poster sessions, covering both normal and pathological roles of TEs, as well as strategies to manage their activity through various scientific approaches.

Article Abstract

The conference "Transposable Elements at the Crossroads of Evolution, Health and Disease" was hosted by Keystone Symposia in Whistler, British Columbia, Canada, on September 3-6, 2023, and was organized by Kathleen Burns, Harmit Malik and Irina Arkhipova. The central theme of the meeting was the incredible diversity of ways in which transposable elements (TEs) interact with the host, from disrupting the existing genes and pathways to creating novel gene products and expression patterns, enhancing the repertoire of host functions, and ultimately driving host evolution. The meeting was organized into six plenary sessions and two afternoon workshops with a total of 50 invited and contributed talks, two poster sessions, and a career roundtable. The topics ranged from TE roles in normal and pathological processes to restricting and harnessing TE activity based on mechanistic insights gained from genetic, structural, and biochemical studies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10680173PMC
http://dx.doi.org/10.1186/s13100-023-00307-4DOI Listing

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