Stentless florence robotic intracorporeal neobladder (FloRIN), a feasibility prospective randomized clinical trial.

Eur J Surg Oncol

Department of Experimental and Clinical Medicine, University of Florence, Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy. Electronic address:

Published: January 2024

AI Article Synopsis

  • The study aimed to evaluate the outcomes of the stentless FloRIN technique used during Robot-Assisted Radical Cystectomy (RARC) for bladder reconstruction, focusing on perioperative and mid-term results.
  • A total of 63 patients participated, with half receiving the stentless procedure; results showed shorter operation times and hospital stays for those without stents, while complications were similar between both groups.
  • The findings suggest that the stentless FloRIN technique is a safe and effective option for bladder reconstruction, demonstrating comparable functional outcomes regarding kidney health over a six-month follow-up.

Article Abstract

Introduction: Aim of the study was to evaluate perioperative, postoperative and mid-term functional outcomes of Florence intracorporeal neobladder (FloRIN) configuration technique performed with stentless procedure.

Materials And Methods: This single institution randomized 1:1 prospective series included consecutive patients treated with Robot-Assisted Radical Cystectomy (RARC) and FloRIN reconfiguration from January 2021 to February 2022. Postoperative complications were graded according to Clavien Dindo classification and divided in early (<30 days from discharge) and delayed (>30 days).

Results: Overall, 63 patients were included in the analysis. Among these 32 (50.8 %) were treated with RARC + stentless FloRIN while 31 (49.2 %) underwent stent placement procedure. No differences were found in terms of baseline characteristics between the two groups. Stentless procedure was associated with significant shorter console time 328 vs 374 min (p = 0.04) and lower estimated blood loss (EBL) 330 vs 350 ml (p = 0.04) comparing to stent group. As regards perioperative features, no significant differences were recorded in terms of canalization (p = 0.58) and time to drainage removal (p = 0.11) while a shorter length of hospital stay was found in case of stentless procedure (p = 0.04). Early postoperative complications Clavien ≥ 3a occurred in 9.3 % and 12.9 % of patients while delayed major complications were recorded in the 3.1 % and 9.6 % of patients treated with stentless and stent FloRIN, respectively (p = 0.09). As regards the mid-term functional outcomes, no differences were found in terms of kidney function loss in both 3rd and 6th month assessment (p = 0.13 and p = 0.14, respectively).

Conclusions: In conclusion, Stentless FloRIN is a feasible and safe IntraCorporeal Neobladder technique, as confirmed by the worthy functional and perioperative outcomes achieved in comparison with the standard FloRIN ureteral management strategy.

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Source
http://dx.doi.org/10.1016/j.ejso.2023.107259DOI Listing

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